About this trial
This study collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients older than 2 months of age who are being evaluated, treated, or enrolled in a clinical trial for cancer at participating sites
Patients with a histologically or cytologically confirmed diagnosis of cancer
Patients without histologically or cytologically confirmed diagnosis of cancer, but for whom approval has been requested and received from the coordinating site study coordinator
Radiographic imaging (computed tomography [CT], magnetic resonance imaging [MRI], etc.)
Disqualifiers
Patients with cancer-like syndromes and/or blood disorders such as systemic mastocytosis, Langerhans cell histiocytosis, chronic eosinophilic leukemia/hypereosinophilic syndrome, lymphomatoid granulomatosis, or monoclonal gammopathy of undetermined significance (MGUS)
Patients with invasive fungal infections
Patients with active and/or uncontrolled bacterial, fungal, or viral infections or who are still recovering from an infection
Actively febrile patients with uncertain etiology of febrile episode
Trial population
Patients undergoing evaluation and/or treatment for cancer
Trial design
Case-only
Prospective
Treatments tested in this trial
Cytology Specimen Collection Procedure
Other interventionProcurement of tissue and blood samples
Treatment groups
Trial outcomes
Primary outcomes
Procurement of tissue and blood specimens for research purposes
Tissues and venous blood will be stored, implanted immediately to generate patient-derived xenografts (which require fresh, viable cells), or placed immediately into in vitro cell culture to generate patient-derived cell lines (which require fresh, viable cells).
Sponsors and contacts
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National Cancer Institute LAO
Lead sponsor
National Cancer Institute (NCI)
Collaborator