Background:
\- Researchers who are studying hairy cell leukemia, and how the disease compares with other disorders, are interested in obtaining additional samples from leukemia patients and healthy volunteers. The investigators are particularly interested in samples from individuals who have diseases that can be treated with a new type of drug called immunotoxin, in which an antibody carrying a toxin binds to a cancer cell and allows the toxin to kill the cell.
Objectives:
\- To collect a variety of clinical samples, including blood, urine, lymph samples, and other tissues, in order to study the samples and develop new treatments for leukemia.
Eligibility:
\- Individuals 18 years of age and older who have been diagnosed with leukemia or other kinds of blood and lymphatic system cancers, or who are healthy volunteers.
Design:
* Individuals who have leukemia will be asked to provide blood, bone marrow, urine, and tumor tissue samples as requested by the researchers. Healthy volunteers will provide only blood and urine samples. * No treatment will be given as part of this protocol.
18 years of age and older
Desire of the individual to submit data and samples for research
Ability to understand and the willingness to sign a written informed consent document.
None
Primary clinical population; normal donors
Case-control
Prospective
Not listed
Tissue Acquisition
Collection of a variety of clinical samples, including blood, urine, lymphapheresis samples, and other tissues and associated data
HCL follow-up
Assess long-term treatment complications and disease outcomes in participants with HCL/HCLv
Click on the lead sponsor to view all of their trials.
