About this trial
The study will adapt and test a combination peer navigation and mHealth approach, Intensive Combination Approach to Rollback the Epidemic in Nigeria (iCARE Nigeria), to improve HIV treatment engagement, medication adherence and viral suppression among YMSM and YTW, ages 15-29.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
HIV seropositive
registered as a patient at one of the collaborating key population (KP)-focused community centers
male sex at birth
identify as YMSM or YTW (or report a history of sex with men)
Disqualifiers
Unable to obtain parental permission if 15 years of age and not emancipated
Trial design
Parallel
Treatments tested in this trial
Combination Peer navigation and mHealth intervention
BehavioralPeer navigation and SMS text message medication reminders (adapted to YMSM and YTW in community outreach-based delivery approach)
Treatment groups
Trial outcomes
Primary outcomes
HIV viral load suppression
Viral load suppression (\<200 copies/mL) at baseline and 24 weeks
Secondary outcomes
Retention in HIV care
Two medical visits in the 24-week study period, with a minimum of 60 days between visits
Medication adherence
Self-reported measure of adherence on visual analogue scale (0-100), with adherence measured as \>or = 90%
Feasibility of intervention
Phone-related and SMS text-related problems resulting in \<10% message failure, measured by text message platform administrative reports
Acceptability of intervention
Acceptability report of \>90% agreement based on Client Satisfaction Questionnaire-8 (CSQ-8)
Sponsors and contacts
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Northwestern University
Lead sponsor
National Institute of Mental Health (NIMH)
Collaborator