Combination of Micropulse Laser With or Without Photodynamic Therapy for Chronic Central Serous Chorioretinopathy
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-70
SponsorBeijing Hospital
About this trial
In this study, patients with chronic central serous chorioretinopathy who were treated by micropulse laser alone or micropulse laser combined with photodynamic therapy without drugs are retrospectively included. The visual acuity changes, subretinal fluid absorption and choroidal characteristics of the two groups are compared 1 to 6 months after treatment. We will also analyze baseline characteristics that influence post-treatment outcomes to identify potential predictors of poor treatment outcomes.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Age >18 years old.
The patient diagnosed with chronic central serous chorioretinopathy with a history of more than 6 months. The diagnostic criteria for chronic CSC were as follows: FFA examination showed leakage of strong fluorescent spots with the extension of angiography time, and late fluorescence accumulation, accompanied by decreased central vision, darkening of vision, and deformable microopia. Fundus examination showed superficial detachment of retinal neuroepithelium in macula.
Patients received single micropulse laser therapy or micropulse laser combined with drug-free photodynamic therapy, and had not received other laser or surgical treatment in the six months prior to treatment.
Patients had follow-up data before and after treatment for 1 month and at least 6 months.
Disqualifiers
Patients with other fundus diseases or refractive interstitial opacity.
During treatment, other treatments other than micropulse laser or drug-free photodynamic therapy were received.
Various reasons led to incomplete patient data.
Trial population
The patient diagnosed with chronic central serous chorioretinopathy with a history of more than 6 months, who received single micropulse laser therapy or micropulse laser combined with drug-free photodynamic therapy.
Trial design
Design model
Case-only
Time perspective
Retrospective
Treatments tested in this trial
Not listed
Trial groups
No trial groups listed
Trial outcomes
Primary outcomes
1
BCVA
Best-corrected visual acuity using logMAR
Time frame
1 month and 6 months2
CRT
Central retinal thickness on OCT
Time frame
1 month and 6 monthsSecondary outcomes
1
SFCT
subfoveal choroidal thickness on OCTA
Time frame
1 month and 6 monthsLocations
Sponsors and contacts
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Source ClinicalTrials.gov
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