Combined Magnetic Stimulation and Ultrasound for Detrusor Overactivity in SCI
ConditionSpinal Cord Injuries
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-80
SponsorShengjing Hospital
About this trial
This clinical trial aims to investigate whether the combination of high-frequency sacral nerve root magnetic stimulation and bladder-directed ultrasound therapy can effectively improve detrusor overactivity (involuntary bladder contractions) and related voiding dysfunctions in patients with spinal cord injury. The main questions it seeks to answer are:
What is the effect of high-frequency sacral nerve root magnetic stimulation on detrusor overactivity and bladder function in patients with spinal cord injury?
What is the effect of bladder-directed ultrasound therapy on detrusor overactivity and bladder wall compliance in patients with spinal cord injury?
Is the combination of these two treatment modalities superior to magnetic stimulation alone?
Eligibility criteria
Qualifiers
Diagnosis of spinal cord injury (SCI) above the sacral level according to the International Standards for Neurological Classification of Spinal Cord Injury (revised 2011), confirmed by CT or MRI;
Detrusor overactivity confirmed by urodynamic study;
No severe urinary system diseases such as tumors, stones, infection, or organic urinary tract obstruction;
No severe hepatic/renal insufficiency, pulmonary, or cardiovascular diseases;
Disqualifiers
Unstable vital signs or critically ill condition;
Severe autonomic dysreflexia;
Presence of metallic implants within 10 cm of the magnetic stimulation treatment area;
Any other diseases or conditions that may interfere with the study outcomes.
Trial design
Treatments tested in this trial
- Transcranial Magnetic Stimulation (TMS) Device /Ultrasound therapy device
Treatment groups
44 Participants
are divided into 2 treatment groupsSponsors and collaborators
Source ClinicalTrials.gov