About this trial
Chest wall tumors are one of the important diseases in thoracic surgery, and surgery is still the main treatment for this disease in clinical practice. Surgery for chest wall tumors requires extensive resection. However, the extensive chest wall defect formed after extensive resection can lead to the destruction of the integrity and stability of the chest wall, thus requiring chest wall reconstruction. The reconstruction of the chest wall after resection has always been a difficult point in chest wall tumor surgery, and the reconstruction of the chest wall bone is a key point in chest wall reconstruction. The goals of successful chest wall bone reconstruction include restoring chest wall rigidity, minimizing chest wall deformities, maintaining lung mechanics, and protecting thoracic organs. At present, traditional reconstruction methods are based on simulating and restoring the anatomical structure of the thoracic spine. For certain special areas of chest wall defects (such as posterior rib and paraspinal tumors), it is difficult to perform residual fixation; At the same time, traditional reconstruction methods suffer from insufficient stability after reconstruction, such as loosening, detachment, displacement, and even fracture. Therefore, it is necessary to design new chest wall reconstruction methods to meet clinical needs.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
18-70 years old, male or female not limited
Anesthesia ASA score I-II
Malignant tumor of soft tissue in the chest
Malignant tumors of ribs, rib cartilage, and sternum
Disqualifiers
Patients with distant metastasis detected during preoperative examination
Inoperable tumor
During the examination, it was discovered that the patient had another type of malignant tumor present
ECOG 4
Trial design
Sequential
Treatments tested in this trial
methods on bone reconstrucion after chest wall tumor resection
Procedure/SurgerySelecting appropriate implants for chest wall bone reconstruction
Treatment groups
Trial outcomes
Primary outcomes
Stability of implants
The occurrence of detachment, displacement, and fracture of implants during follow-up in patients undergoing chest wall tumor surgery after receiving a new reconstruction method
Secondary outcomes
Respiratory discomfort
Patient's respiratory discomfort in a calm state or walking state, measured as mild, moderate, or sereve after reconstruction surgery
Postoperative complications
Pulmonary infection, atelectasis, pleural effusion, respiratory failure, postoperative drainage tube removal time, length of hospital stay
Complications of implants
Fracture, displacement, infection, and compatibility of implants
Postoperative physical function status
Karnofsky scoring scale
Locations
Sponsors and contacts
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