Comparing CCI and POSSUM for Predicting Oncogynecologic Surgery Complications

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexFemale
Age18+
SponsorMahidol University

About this trial

With the global rates of gynecologic cancers on the rise, optimizing perioperative care is imperative. Accurate risk prediction is essential for enhancing patient care, directing preoperative interventions, and facilitating informed decision-making in oncology. This research compares two widely-used risk assessment tools: the Charlson Comorbidity Index (CCI) and the Physiological and Operative Severity Score for the enUmeration of Mortality and Morbidity (POSSUM), in predicting perioperative outcomes. The CCI predominantly addresses comorbidities, providing simplicity and broad applicability, while POSSUM incorporates both physiological and operative factors for a more comprehensive risk assessment. Despite their application across various surgical specialties, the specific utility of these tools in onco-gynecologic surgery remains insufficiently explored. The study aims to evaluate the effectiveness of CCI and POSSUM in predicting perioperative complications, with a focus on the incidence of these complications, length of hospital stay, and 30-day mortality. The implementation of these risk tools may enhance multidisciplinary risk management, thus improving patient outcomes in gynecologic oncology surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age > 18 years

Patient underwent elective onco-gynecologic surgery

Disqualifiers

Patient required emergency surgery from any indication

Patient chart that not contained primary outcome data eg. absent of the anesthetic record

Trial population

Patient aged \>,= 18 years, underwent elective onco-gynecologic surgery.

Trial design

Design model

Case-only

Time perspective

Retrospective

Treatments tested in this trial

  • CCI score

    Other intervention

    Charlson comorbidity index included age and medical conditions

  • POSSUM score

    Other intervention

    POSSUM included physical status and laboratory investigation

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

Comparison of CCI and POSSUM to predict perioperative complications

To compare the prediction of perioperative anesthetic and surgical morbidity by the Charlson-Comorbidity Index versus POSSUM score in patients undergoing elective onco-gynecological surgery

Time frame
from the date of starting surgery to the date of hospital discharge, up to 30 days

Secondary outcomes

1

Intraoperative hypotension

Intraoperative complications related to anesthesia: intraoperative hypotension

Time frame
Within 24 hours from starting of surgery
2

Quantity of intraoperative blood loss

Intraoperative blood loss estimated by anesthetic personnel

Time frame
Within 24 hours from starting of surgery
3

Rate of blood transfusion

Intraoperative rate and amount of packed red cells blood transfusion and/or blood component

Time frame
Within 24 hours from starting of surgery
4

Rate of vasopressor usage

Intraoperative rate and amount of vasopressor usage

Time frame
from the time staring of surgery to the time of finishing surgery, up to 12 hours

Other outcomes

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