Comparing Photodisinfection of Chitosan NP Enriched ICG Over ICG as Adjunct to OFD: RCT

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age30-55
SponsorKrishnadevaraya College of Dental Sciences & Hospital

About this trial

The current study is a prospective randomised study-Comparison of photodisinfection with chitosan nanoparticles enriched indocyanine green over indocyanine green as an adjunct to open flap debridement in the management of stage II/III grade B/C periodontitis.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Systemically healthy subjects

Age group 30-55yrs.

Diagnosed with Stages II/III grade B/C periodontitis.

Presenting with persistent pocket depth ≥5mm after initial non-surgical therapy.

Disqualifiers

Subjects on antibiotic therapy within last six months of enrollment

Previous history of periodontal surgery

Allergy to drugs and materials used in this study

Pregnant woman

Trial design

Design model

Parallel

Treatments tested in this trial

  • PHOTODYNAMIC THERAPY

    Procedure/Surgery

    Respective photosensitive dye solution is applied on to the surgical site, including all the root surfaces. Vacuum suction is used to remove the excess dye from the site and to prevent ingestion of the dye solution The dye is activated with 810nm diode laser with continuous wave frequency and power of 0.3 W with 400 µm fiber tip for 20 seconds/spot. After this, the area is irrigated with saline.

Treatment groups

24 Participants
are divided into 2 treatment groups
Group A: test groupExperimental treatment 1 intervention
Group B: Control groupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

MICROBIAL ANALYSIS

LEVELS OF P. GINGIVALIS

Time frame
3 MONTHS

Secondary outcomes

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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