In this study the investigators aimed to explore the antibiofilm effect of fluoride varnish loaded with titania nanoparticles synthesized from moringa oleifera leaves extract vs conventional fluoride varnish in multibracket fixed orthodontic patients.
Patients planned for fixed orthodontic treatment.
Patients within age group 16-30 years.
Patient with no history of previous orthodontic treatment.
Patients with no active periodontal diseases.
Patient undergoing any antibiotic therapy.
Patients with any craniofacial abnormality.
Patient with mixed dentition
Parallel
Fluoride varnish
Procedure/SurgeryGroup A will receive conventional fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.
Novel titania nanoparticle infused fluoride varnish
Procedure/SurgeryGroup B will receive topical application of titania nanoparticle infused fluoride varnish for antiplaque effects.Plaque will be assessed quantitatively by modified plaque index.
To compare the plaque inhibitory effect of titania nanoparticle infused fluoride varnish and conventional fluoride varnish in fixed orthodontic patients.
Plaque will be assessed quantitatively by modified plaque index.
To measure plaque bacterial load and pH following application of titania nanoparticle infused and conventional fluoride varnish in fixed orthodontic patients.
Bacterial colonies will be morphologically identified and counted as Colony Forming Units (CFU) using a colony counting grid.
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