Health TrialsbyHealthPanel

Comparing the Olfactory Perception of a Fragrance-Loaded SpECs Over Time

ConditionPerception, Self
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
Age18-45
SponsorRoyal College of Surgeons in Ireland - Medical University of Bahrain

About this trial

The human olfactory system plays a crucial role in sensory perception, influencing emotional states, memory, and interpersonal interactions(1). Fragrance durability and intensity are critical factors in the evaluation of perfumes and other scented products. The ability of fragrance formulations to maintain consistent scent intensity over time is a major contributor to a product's overall efficacy and consumer satisfaction,

Primary Aim To compare the perceived strength of a topical fragrance delivered via SpECs across a period of 8 hours using subjective ratings by participants and an independent examiner.

Objectives

1. To investigate whether the encapsulated fragrance intensity, as perceived by participants, decreases less over time compared with fragrance alone, after application to the skin. 2. To investigate whether the encapsulated fragrance intensity, as perceived by an independent examiner, decreases less over time compared with fragrance alone, after application to the skin.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Females aged between 18 and 45 years.

No history of olfactory impairment, allergies to pollen or fragrances, or skin conditions.

Disqualifiers

Current use of medications that affect olfactory function (e.g., antihistamines).

Pregnancy or breastfeeding.

Any active upper respiratory tract infection within 2 weeks of the clinical trial

Any known skin allergy.

Trial design

Design model

Crossover

Treatments tested in this trial

  • Fragrance

    Other intervention

    this intervention involves the controlled use of specific fragrance with and withouth SpECs grains

Treatment groups

10 Participants
are divided into 2 treatment groups
Group A: Group A: Fragrance loaded with a concentration of SpECs grains.Experimental treatment 1 intervention
Group B: Group B: Fragrance loaded without SpECs grainsActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Sustained olfactory perception over time.

The study will determine whether fragrance-loaded SpECs provides a sustained olfactory perception over time.

Time frame
6 hour period- 4 timepoints

Secondary outcomes

1

Impact of SpECs concentration on fragrance

Insights into the impact of SpECs concentration on fragrance strength and duration will be obtained.

Time frame
6 hour period- 4 timepoints
2

alignment between participant's and independent examiner's ratings

The alignment between participant's subjective ratings and the independent examiner's ratings will help validate the reliability of self-assessments in olfactory studies.

Time frame
6 hour period- 4 timepoints

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Royal College of Surgeons in Ireland - Medical University of Bahrain

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: