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Comparision of Clinical Efficacy of Immediate Implants With T-PRF and Bone-graft Versus PRF and Bone-graft

ConditionDental Implants
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-55
SponsorKrishnadevaraya College of Dental Sciences & Hospital

About this trial

The normal architecture of the alveolar process is altered by periodontitis, which also causes the loss of alveolar bone surrounding the teeth. Untreated periodontitis may cause teeth to become mobile and leads to loss of teeth.

In such cases, one of the treatment modalities is extraction of the tooth and placement of immediate implant which reduces the waiting period. And due to the resorption of alveolar ridge the bone graft will be used along with T-PRF and PRF.

So this study aims at the placement of immediate implants along with T-PRF with bone graft and PRF with bone graft.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients between 18-55 years of age.

Presence of non-restorable teeth (maxillary or mandibular) due to trauma, decayed, mobility, root resorption, root stumps, root fracture, over retained deciduous tooth, endodontic or periodontal failure in whom immediate implants can be placed.

Good oral hygiene.

Good patient compliance.

Disqualifiers

Systemic complications (uncontrolled diabetes and severe cardiovascular or infectious diseases).

Intravenous and oral bisphosphonate therapy.

Patients who are psychologically unable to participate.

Pregnant and lactating participants with bone diseases

Trial design

Design model

Parallel

Treatments tested in this trial

  • Immediate implant surgery with T-PRF and xenograft

    Procedure/Surgery

    A mucoperiosteal flap will be raised and atraumatic extraction will be done. An immediate implant with T-PRF and xenograft will be placed according to the standard protocol. The surgical wound closure will be coapted with mattress and single interrupted sutures

  • Immediate implant surgery with PRF and xenograft

    Procedure/Surgery

    A mucoperiosteal flap will be raised and atraumatic extraction will be done. An immediate implant with PRF and xenograft will be placed according to the standard protocol . The surgical wound closure will be coapted with mattress and single interrupted sutures

Treatment groups

20 Participants
are divided into 2 treatment groups
Group A: in 10 sites immediate implant will be placed along with T-PRF and xenograftExperimental treatment 1 intervention
Group B: in 10 sites immediate implants will be placed with PRF and xenograftActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Marginal Bone Level Using RVG and Grid.

Marginal bone level measured .

Time frame
Baseline , 3 months , 9 months
2

Soft tissue healing

Soft tissue healing will be assessed using Wachtel-et-al 2009 classification

Time frame
Baseline ,3 months , 9 months
3

Bone fill using RVG with grid

Measuring the Bone fill by formula Linear bone growth/depth of original bone defect

Time frame
3 months , 9 months
4

Bone dimensions using CBCT

Extent of bone dimensions is measured through CBCT

Time frame
9 months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Krishnadevaraya College of Dental Sciences & Hospital

Lead sponsor

Source ClinicalTrials.gov

This trial is not recruiting at the moment. You can still explore other options: