Comparison Between 3 Conservative Surgeries for Placenta Accreta Spectrum

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexFemale
AgeNot listed
SponsorAssiut University

About this trial

Comparison between modified one-step surgery vs. Segment Resection vs. placental bed suturing for management of placenta accreta spectrum

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

pregnant women with placenta accreta spectrum

Disqualifiers

Patients refuse to share in the study

Pregnant < 28 weeks

Trial design

Design model

Single group

Treatments tested in this trial

  • Modified one-step surgery

    Procedure/Surgery

    transverse uterine incision is made at the upper border of the placenta without cutting through the placenta, then fetal delivery. A tourniquet is first put into the para-cervical area (using a Foley 12-F catheter) to stop active bleeding, and bilateral uterine artery ligation (using Chromic 1/0) is performed, followed by manual placental removal . Myometrial resection is performed if the remaining lower uterine segment of the healthy myometrium measures more than 2 cm. Suture of both edges of the uterine incision and hemostatic sutures of the placental bed surface (using chromic suture 1/0) are performed. Finally, the tourniquet is released and a transverse B-Lynch compression suture is made

  • Segment Resection

    Procedure/Surgery

    transverse uterine incision was applied just above the upper border of involved uterine wall . And the fetus was extracted from this incision and the umbilical cord was clamped. In order to decrease hemorrhage, anterior branches of hypogastric arteries were ligated bilaterally. urinary bladder dissection from anterior uterine wall is done. Then the involved segment is resected by leaving placental free tissue medially to the uterine arteries, below transverse uterine incision and above the cervix. Resection was made by scissors or cautery and bleeding from the borders was controlled by ring forceps.

  • Placental bed suturing

    Procedure/Surgery

    After the separation of the placenta, all bleeding areas are clamped with several curved ovarian forceps. After the mechanical hemostasis of the lower uterine segment has been achieved, the remaining small amounts of placental fragments are removed by instrument. The clamps are removed sequentially, and the vesicouterine interface and all spaces are sutured with superficial stitches under the guidance of the surgeon's fingers. These superficial continuous sutures are not very deep. Cho sutures are used to achieve comlete hemostasis.

Treatment groups

42 Participants
are divided into 3 treatment groups
Group A: Modified one-step surgeryExperimental treatment 1 intervention
Group B: Segment ResectionExperimental treatment 1 intervention
Group C: Placental bed suturingExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Intraoperative Blood loss

Increased blood loss means bad outcome

Time frame
24 hours

Secondary outcomes

Other outcomes

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