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Comparison Between Individualized PEEP Ventilation Guided by Driving Pressure and Conventional Lung Protective Strategy in Obese Patients Undergoing Laparoscopic Bariatric Surgery

ConditionsObese Patients With Bariatric SurgeryLung Ultrasound Score
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-60
SponsorMahmoud Gamal Ahmed Arakeeb

About this trial

this study to compare the ventilation in obese patients either using Driving pressure ventilation technique or conventional protective lung strategy all by using Lung ultrasound score

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

patients who have a BMI 30-40 kg/m2

American Society of Anesthesiologists (ASA) physical status II or III

patients aged between 18 and 60 years,

patients scheduled to undergo laparoscopic bariatric surgeries.

Disqualifiers

patients' refusal to participate in the study,

previous history of thoracic surgery,

Patients with a history of chest disease (COPD, emphysema, or pneumothorax),

Patients with abnormal pre-operative chest radiographs, such as pneumonia and pleural effusion,

Trial design

Design model

Parallel

Treatments tested in this trial

  • lung ultrasound

    Device

    The lung ultrasound score between 0 and 3 (0 = normal A lines, 1 = multiple separated B lines, 2 = coalescing B lines or light beam, 3 = consolidation). The aeration score will be built by the sum of the scores of the 12 segments, with a minimum of 0 and a maximum of 36 according to the aeration loss.

Treatment groups

60 Participants
are divided into 3 treatment groups
Group A: Group D (Driving pressure)Experimental treatment 1 intervention
Group B: Group L (Lung protective strategy)Experimental treatment 1 intervention
Group C: Group P (Physiological PEEP)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

The change in lung ultrasound score

The primary outcome will be the change in Lung Ultra Sound Score between 0 and 3 (0 = normal A lines, 1 = multiple separated B lines, 2 = coalescing B lines or light beam, 3 = consolidation) from the base line.

Time frame
Periprocedural

Secondary outcomes

1

Lung compliance

Lung compliance is a measure of the expansion of the lung.

Time frame
Periprocedural
2

Hemodynamic parameter as oxygen saturation

Time frame
Periprocedural
3

Hemodynamic parameter as Heart rate

Time frame
Periprocedural
4

Hemodynamic parameter as Mean arterial blood pressure

Time frame
Periprocedural

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Mahmoud Gamal Ahmed Arakeeb

Lead sponsor

Tanta University

Sponsor institution

Source ClinicalTrials.gov
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