About this trial
Ultrasound (US) guided Erector spinae plane block (ESPB) as a new trunchal fascial plane block technique was proposed in 2016. US guided ESPB has aroused the interest of many nerve block experts. The goal of this study is to evaluate the effect of US guided ESPB versus (VS) intravenous Dexmedotomidine on postoperative analgesia and intra operative hemodynamic parameters in lumbar spine surgeries.
The aim of this study is to compare the efficacy of ESPB to intravenous Dexmedetomidine in patients who are undergoing elective lumber spine surgeries regarding the effect on postoperative analgesia and intra operative hemodynamic parameters.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.
Disqualifiers
patients under 18 years of age.
History of Allergic reactions to study drugs.
Opioid or analgesic abuse, and chronic treatment with opioids, or nonsteroidal anti-inflammatory drugs.
History of bleeding tendency or coagulopathy
Trial design
Parallel
Treatments tested in this trial
Ultrasound erector spinae plane block
Procedure/SurgeryPatients will be subdivided randomly into two groups (15 patients each) using computer generated random numbers with closed envelopes: Group U (15 patients):will receive bilateral US guided single shot ESPB, 30 ml of bupivacaine 0.25% on each side after induction of anesthesia.
dexamedotomidine infusion after induction of anesthesia
Procedure/SurgeryPatients will be subdivided randomly into two groups (15 patients each) using computer generated random numbers with closed envelopes: Group D (15 patients):will receive the study drug infusion (Dexmedetomidine) after induction of anesthesia.
Treatment groups
Trial outcomes
Primary outcomes
(VAS) during the 1st 24 hours
Pain will be assessed on admission and at 2, 4, 8, 12 and 24 hours at rest and with passive flexion of hip and knee joint using visual analogue scale (VAS) ranging from 0 for no pain to 10 for worst pain.
Sponsors and contacts
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