Comparison Between Ultrasound Guided Erector Spinae Plane Block and Dexmedotomidine in Lumber Spine Surgeries.

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorAin Shams University

About this trial

Ultrasound (US) guided Erector spinae plane block (ESPB) as a new trunchal fascial plane block technique was proposed in 2016. US guided ESPB has aroused the interest of many nerve block experts. The goal of this study is to evaluate the effect of US guided ESPB versus (VS) intravenous Dexmedotomidine on postoperative analgesia and intra operative hemodynamic parameters in lumbar spine surgeries.

The aim of this study is to compare the efficacy of ESPB to intravenous Dexmedetomidine in patients who are undergoing elective lumber spine surgeries regarding the effect on postoperative analgesia and intra operative hemodynamic parameters.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

ASA I and II patients. aged 18 to 50 years. 70 to 80 kg.

Disqualifiers

patients under 18 years of age.

History of Allergic reactions to study drugs.

Opioid or analgesic abuse, and chronic treatment with opioids, or nonsteroidal anti-inflammatory drugs.

History of bleeding tendency or coagulopathy

Trial design

Design model

Parallel

Treatments tested in this trial

  • Ultrasound erector spinae plane block

    Procedure/Surgery

    Patients will be subdivided randomly into two groups (15 patients each) using computer generated random numbers with closed envelopes: Group U (15 patients):will receive bilateral US guided single shot ESPB, 30 ml of bupivacaine 0.25% on each side after induction of anesthesia.

  • dexamedotomidine infusion after induction of anesthesia

    Procedure/Surgery

    Patients will be subdivided randomly into two groups (15 patients each) using computer generated random numbers with closed envelopes: Group D (15 patients):will receive the study drug infusion (Dexmedetomidine) after induction of anesthesia.

Treatment groups

30 Participants
are divided into 2 treatment groups
Group A: group UExperimental treatment 1 intervention
Group B: group DExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

(VAS) during the 1st 24 hours

Pain will be assessed on admission and at 2, 4, 8, 12 and 24 hours at rest and with passive flexion of hip and knee joint using visual analogue scale (VAS) ranging from 0 for no pain to 10 for worst pain.

Time frame
24 HOURS

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

This trial is not recruiting at the moment. You can still explore other options: