The goal of this clinical trial is to find the difference in immune response between two types of regional anesthesia in female patients suffering from breast cancer.
The main question it aims to answer is there a difference in the immune response between paravertebral block and erector spinal plane block.
Hypothresis of the study is that paravertebral block with propofol induces less immune response in surgical treatment of breast cancer patients than erector spinal plane block.
Participants will be asked to sign the informant consent. They will be given either paravertebral block or erector spinae plane block with general anesthesia using propofol. Their venous blood will be taken 1 hour prior surgery and 24 and 48 hours after surgery.
ASA I and ASA II status, normal BMI
ASA III and ASA IV status, coagulopathy, chronic opioid use, diabetes, local infection of the skin
Parallel
Regional Anesthetic Injection
Procedure/SurgeryDraw of venous blood and application of paravertebral and erector spinae plane block
Blood draw for the laboratory assessment
Procedure/SurgeryDraw of venous blood 24 hours after surgery
Blood draw for the laboratory assessment
Procedure/SurgeryBlood draw 48 hours after surgery
Immune response in two different regional anesthesia techniques
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This trial is not recruiting at the moment. You can still explore other options:
