To explore the relationship between perioperative blood pressure and catecholamine concentrations in adrenal venous blood and peripheral venous blood in hypertensive patients with primary aldosteronism (PA) who underwent percutaneous selective adrenal artery embolization (SAAE). In order to elucidate the related phenomena and possible mechanisms of blood pressure fluctuations caused by SAAE treatment in hypertensive patients with PA.
Age ≥18 years with no gender restrictions.
Adherence to the "Primary Aldosteronism" Diagnosis and Treatment Guidelines, confirmed diagnosis of primary aldosteronism following rigorous drug washout, and identification as either aldosteronoma or idiopathic aldosteronism via adrenal vein blood sampling.
Blood pressure metrics that satisfy any of the subsequent conditions: a) Clinic-recorded blood pressure ≥140/90mmHg; b) 24-hour ambulatory blood pressure monitoring results displaying average blood pressure >130/80 mmHg or daytime readings >135/85 mmHg.
Adrenal CT scan revealing adrenal hyperplasia, nodular formations, or no significant morphological deviations.
Patients diagnosed with primary hypertension or secondary hypertension attributed to other etiologies.
Female participants who are presently pregnant, lactating, or with intentions to conceive within the forthcoming year.
Presence of significant systemic diseases, with particular attention to hepatic and renal dysfunction.
Pronounced allergic reaction to contrast agents.
Hypertensive patients with a definite diagnosis of primary aldosteronism who agree to undergo percutaneous selective adrenal artery embolization.
Cohort
Prospective
Selective adrenal artery embolization
Procedure/SurgeryPercutaneous selective adrenal artery embolization in patients with primary aldosteronism
Invasive blood pressure
Auxiliary check
24-hour dynamic blood pressure
Auxiliary check
Plasma Norepinephrine
Biochemical indicators
Plasma Adrenaline
Biochemical indicators
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