Comparison of Efficacy of Microneedling With Platelet Rich Plasma Vs Microneedling With Topical Insulin in the Treatment of Acne Scars

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorKhyber Teaching Hospital

About this trial

This study compares the outcome of two procedures for the treatment of atrophic acne scars.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

Patient with active acne or other skin conditions (e.g eczema , psoriasis). Patients on oral or topical retinoids. Pregnant or lactating Mothers. Patients with recurrent herpes simplex infection. Previous Hx of keloids / hypertrophic scarring. Deranged blood glucose levels. Bleeding disorders

Trial design

Design model

Parallel

Treatments tested in this trial

  • Microneedling with autologous Platelet Rich Plasma

    Procedure/Surgery

    Patients in group A will undergo Microneedling with autologous PRP

  • Microneedling with topical insulin

    Procedure/Surgery

    Patients in group B will undergo Microneedling with Topical insulin ( regular).

Treatment groups

116 Participants
are divided into 2 treatment groups
Group A: Group A , Microneedling with autologous PRPExperimental treatment 1 intervention
Group B: Group B , Microneedling with Topical insulinExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Efficacy of treatment

Efficacy will be determined by using the Goodman and Baron's Scarring Grading System as" Percentage of decrease in acne scar grade" i.e calculated through subtracting post treatment grade from pre treatment grade and then multiplying it with 100 in both treatment groups .

Time frame
6 months

Secondary outcomes

Other outcomes

Sponsors and contacts

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