Comparison of High Flow Nasal Oxygen and Nasal Cannula in Burn Patients Under Sedation
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAnkara City Hospital Bilkent
About this trial
Burn-related pain is severe and often difficult to manage. Burn patients often require high doses of opioids and anxiolytics. Anesthetic agents used during sedation such as benzodiazepines, propofol and opioids can cause respiratory depression, predisposing patients to hypoventilation and hypoxemia due to airway obstruction. Oxygen is administered to patients with a standard nasal cannula during sedation. High Flow Nasal Oxygen (HFNO) helps to improve the oxygenation of patients with respiratory distress by delivering high flow humidified oxygen through the nasal cannula at a high rate of up to 40-70 liters per minute. The aim of this study was to compare the effects of HFNO and nasal oxygen therapy in preventing hypoxemia in deeply sedated burn patients.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
None
Disqualifiers
Intubation
Tracheostomies
Need for oxygen therapy due to preexisting disease
Pregnancy
Trial population
Patients scheduled for burn treatment under sedation in Ankara City Hospital's Burn Center will be included
Trial design
Design model
Case-control
Time perspective
Prospective
Treatments tested in this trial
Not listed
Trial groups
70 Participants
are grouped into 2 trial groupsGroup A: Group 1: Standard nasal oxygen therapy
Group B: Group 2: High-flow nasal oxygen therapy (HFNO)
Trial outcomes
Primary outcomes
1
Oxygen saturation SpO2 levels of the cases in %
Each patient will be monitored with an oxygen saturation probe and SpO2 levels of the cases will be recorded before induction of sedation and every 5 minutes, throughout the procedure. Hypoxemia will be detected.
Time frame
Oxygen saturation levels will be recorded before induction and every 5 minutes throughout the procedure.Secondary outcomes
1
Number of interventions over procedure time
In case of apnea or desaturation, airway interventions will be performed and recorded throughout the procedure.
Time frame
Number of maneuvers performed throughout the procedure.Other outcomes
1
Systolic, diastolic and mean blood pressures will be recorded in mmHg
Before induction patients will be monitored, and systolic, diastolic and mean blood pressures will be recorded before induction and every 5 minutes throughout the procedure.
Time frame
Blood pressure monitorization will be performed induction and every 5 minutes throughout the procedure.2
Heart beat will be recorded in beats per minute
Heart beats will be recorded before induction and every 5 minutes throughout the procedure.
Time frame
Heart beat monitorization will be performed before induction and every 5 minutes throughout the procedure.Sponsors and contacts
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Source ClinicalTrials.gov