The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and potentially safer option. A previous study showed that PRP was as effective as ESI in treating this condition, without major complications.
This study aims to compare these two treatments over the long term (2 years).
Diagnosis of unilateral resistant LRP associated with a herniated disc on MRI images. (Diagnosis of resistance after 6 weeks of appropriate medical treatment).
Patients with infections,
Patients who have had previous percutaneous corticosteroid injections,
Patients undergoing systemic corticosteroid treatment,
Patients with immune deficiencies,
Parallel
Epidural Steroid Injection
Procedure/SurgeryIntervention consists of interlaminar CT guided epidural steroid injection
Epidural platelet-rich plasma injection
Procedure/SurgeryIntervention consists of interlaminar CT guided epidural platelet-rich plasma injection after recovery of plasma by blood sampling and centrifugation
Functional ability
Oswestry Disability Questionnaire ranging from 0 to 100%
Pain evaluation
Numerical pain rating scale (NRS): intensity of combined pain in the legs and back ranging from 0 to 10
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