About this trial
Evidence of implementation of laparoscopic total gastrectomy (LTG) for locally advanced gastric cancer (GC) remains inadequate. This study aimed to compare short- and mid-term outcomes of LTG versus open total gastrectomy (OTG) for cT2-4a GC.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Pathologic finding by gastric endoscopy: confirmed gastric adenocarcinoma
Age: 18 - 80 year old
Tumor required total gastrectomy for radical treatment
Preoperative cancer stage (CT scan stage): cT2-4aNanyM0
Disqualifiers
Concurrent cancer or patient who was treated due to other cancer before the patient was diagnosed gastric cancer
Bulky lymph node andd/or Para-aortic lymph node metastasis
Combined esophagectomy due to invading to the esophagus
Pregnant patient
Trial design
Parallel
Treatments tested in this trial
Laparoscopic gastrectomy
Procedure/SurgeryGastrectomy with laparoscopic approach
Treatment groups
Trial outcomes
Primary outcomes
3 year overall survival by Kaplan Mayer
The percentage of people in this study who are alive three years after surgery
3 year relapse-free survival by Kaplan Mayer
The percentage of people in this study who are alive without recurrence three years after surgery.
Secondary outcomes
operative morbidity
The rate of postoperative bleeding and the rate of postoperative leakage
operative mortality
The rate of postoperative dead
operative time
The duration of a surgical procedure in minutes.
Resected lymph nodes
The number of lymph nodes harvested after surgery
Sponsors and contacts
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