Comparison of LASER Therapy and Desensitizing Agents in Dentinal Hypersensitivity

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-50
SponsorKemia Gul

About this trial

This study evaluates the effectiveness of laser therapy versus desensitizing agents in reducing pain among participants with dentinal hypersensitivity conducted in Saidu College of Dentistry. Pain will be measured at baseline, immediately post-treatment, one week, and three months using the Visual Analog Scale (VAS)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Participants aged 18-50 years with a preoperative VAS score of ≥2 for dentinal hypersensitivity.

Participants with sensitivity due to gingival recession, cervical abrasion, or enamel erosion.

Participants with good systemic health.

Minimum of two hypersensitive teeth present in two different quadrants.

Disqualifiers

Teeth with caries, defective restorations, or cervical defects > 2 mm (may affect sensitivity measurements).

Periodontal surgery or deep periodontal pockets (> 6 mm) within the past three months (potential influence on periodontal health and sensitivity).

Participants using desensitizing toothpaste within the past three months (could interfere with study outcomes).

Presence of gross oral pathology or systemic diseases (e.g., eating disorders, chronic diseases, uncontrolled metabolic conditions) (may alter oral health status).

Trial design

Design model

Parallel

Treatments tested in this trial

  • Glutaraldehyde-Based Desensetizing Agent

    Drug

    A glutaraldehyde-based desensitizing agent applied to the cervical area of affected teeth using a micro-brush, left undisturbed for 30 seconds, and air-dried. Both interventions aim to reduce pain associated with dentinal hypersensitivity by either occluding dentinal tubules or reducing nerve excitability

  • Low Level Laser Therapy

    Device

    Low-level laser therapy (LLLT) using a diode laser set to a low power level (e.g., 100 mW, continuous wave mode). Each affected tooth will be treated for three minutes, targeting apical, cervical, and middle points

Treatment groups

172 Participants
are divided into 2 treatment groups
Group A: Arm 1 (Desensitizing Agent)Active comparator 1 intervention
Group B: Arm 2 (Laser Therapy)Experimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Change in pain intensity: Visual Analog Scale

After intervention there is a possibility of change in pain intensity in Dentinal Hypersensitivity

Time frame
Immediately post-treatment, one week, and three months

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Kemia Gul

Lead sponsor

College of Physicians and Surgeons Pakistan

Sponsor institution

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