Comparison of Long-term Survival and Quality of Life After Minimally Invasive Esophagectomy Versus Open Esophagectomy

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorQilu Hospital of Shandong University

About this trial

To analyze and compare the long-term recurrence-free survival rate, overall survival rate and quality of survival after minimally invasive esophagectomy and open esophagectomy, and to conduct subgroup analysis according to the type of esophageal cancer and pathological stage, etc., and to explore more deeply the differences between minimally invasive esophagectomy and open esophagectomy in terms of the benefits for different types of patients, so as to provide reference for the selection of the clinical surgical methods. We will also use the available data to analyze the influence of other factors on patients\' long-term survival after surgery.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients who had undergone esophageal cancer resection at the Department of Thoracic Surgery, Qilu Hospital, Shandong University, between 2013 and 2021, with pathology results confirming esophageal squamous carcinoma, adenocarcinoma, or other malignant tumors.

The surgery was successfully completed, the patient was safely discharged from the hospital, the postoperative follow-up was successful, and if the follow-up patient died, his or her death was due to natural causes.

Disqualifiers

None

Trial population

Patients who had undergone esophageal cancer resection at the Department of Thoracic Surgery, Qilu Hospital, Shandong University, between 2013 and 2021.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

1,474 Participants
are grouped into 2 trial groups
Group A: Minimally invasive esophageal cancer resection group
Group B: Open esophageal cancer resection group

Trial outcomes

Primary outcomes

1

Survival Information

Dead or alive 5 years after surgery

Time frame
From enrollment to 5 years after surgery
2

score of Quality of life

Measured with EORTC QLQ-OES18 Quality of Life Questionnaire

Time frame
From enrollment to 5 years after surgery

Secondary outcomes

1

Recurrence or metastasis

Imaging, lab results

Time frame
From enrollment to 5 years after surgery

Other outcomes

Locations

1

Map coordinates are unavailable for these locations. Locations are shown below instead.

Qilu Hospital of Shandong University Status unavailable 250012, Ji'nan, ShandongChinaChina

Sponsors and contacts

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