Lower EEG alpha band power is currently extensively studied as a potential biomarker of brain vulnerability. No previous study has evaluated whether there was a difference in EEG power spectrum ranges between propofol and sevoflurane, the two main anesthetic agents for maintenance of general anesthesia, in order to define a cut-off value for the prediction of a higher risk of postoperative delirium.
* Primary objective: comparison of EEG alpha power (dB) during maintenance of anesthesia with propofol and sevoflurane using data available in the NeuroSense® depth-of-anesthesia monitoring * Secondary objectives: comparison of other EEG frequency bands during maintenance of anesthesia with propofol and sevoflurane using data from the NeuroSense® depth-of-anesthesia monitoring
Capable to give informed consent
French-speaking patients
Need for a premedication with benzodiazepine before anesthesia
Reduced left ventricular ejection fraction (< 50%) or underlying cardiac pathology requiring a more balanced anesthesia (administration of benzodiazepine and/or ketamine during anesthesia)
Preoperative MoCA score < 26/30 (for patients > ou = 55 years old)
Patients treated with anti-epileptic drugs
Parallel
Maintenance of general anesthesia by Propofol
Other interventionMaintenance of general anesthesia for simple electrophysiological procedures
Maintenance of general anesthesia by Sevoflurane
Other interventionMaintenance of general anesthesia for simple electrophysiological procedures
Alpha-band power
Power in decibels from the NeuroWave monitor under general anesthesia
Delta-band power
Power in decibels from the NeuroWave monitor
Thêta-band power
Power in decibel from the NeuroWave monitor
Bêta-band power
Power in decibel from the NeuroWave monitor
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