Comparison of Minimum Flow and Low Flow Desflurane Anesthesia in Robotic Assisted Laparoscopic Abdominal Surgery

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorAnkara City Hospital Bilkent

About this trial

This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery. The comparison will be based on hemodynamic and respiratory parameters. The secondary aim of our study is to compare the two different fresh gas flow methods in terms of inhalation agent consumption and soda lime consumption.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Patients undergoing robotic-assisted abdominal surgery

Disqualifiers

serious cardiac, respiratory, hepatic, renal, or mental disorders;

hearing problems;

anxiety, depression, or other psychiatric conditions;

patient's request to leave the study

Trial population

Patients undergoing robotic-assisted abdominal surgery

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • blood gas analysis

    Other intervention

    1. Airway pressure (P plateau, Ppeak) values are taken from the anesthesia device data, 2. BIS (from routine BIS monitoring) 3. Temperature (routinely from pharyngeal temperature probe), 4. Oxygen saturation (routinely from the patient monitor) 5. End-tidal CO₂, 6. inspiratory O₂ concentration, 7. Inspiratory CO2 concentration, 8. inspiratory and expiratory desflurane concentrations, 9. tidal volume, 10. MAC is routinely obtained from anesthesia device data. 11. Blood Gas Analysis (COHgb, Ph, PO2, PCO2, SaO2, HCO3, Base deficit, glucose, lactate)

Treatment groups

70 Participants
are divided into 2 treatment groups
Group A: Group 11 intervention
Group B: Group 21 intervention

Trial outcomes

Primary outcomes

1

inspiratory O2 concentration

inspiratory O2 concentration is measured from anesthesia machine monitor

Time frame
from beginning of anesthesia induction to the end of anesthesia (during periopertaive period)
2

partial oxygen pressure

PO2 from blood gas analysis

Time frame
from beginning of anesthesia induction to the end of anesthesia (during periopertaive period)

Secondary outcomes

1

desflurane consumption

desflurane consumption

Time frame
3th hour
2

changes in liver and kidney function tests from the preoperative values to 48 hours postoperative

to determine the changes in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine from the preoperative values to 48 hours postoperative

Time frame
postoperative 1st day

Other outcomes

Sponsors and contacts

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