About this trial
This study aims to compare the use of low fresh gas flow (1 L/min) desflurane anesthesia with minimum fresh gas flow (0.5 L/min) desflurane anesthesia in patients undergoing robotic-assisted abdominal surgery. The comparison will be based on hemodynamic and respiratory parameters. The secondary aim of our study is to compare the two different fresh gas flow methods in terms of inhalation agent consumption and soda lime consumption.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Patients undergoing robotic-assisted abdominal surgery
Disqualifiers
serious cardiac, respiratory, hepatic, renal, or mental disorders;
hearing problems;
anxiety, depression, or other psychiatric conditions;
patient's request to leave the study
Trial population
Patients undergoing robotic-assisted abdominal surgery
Trial design
Cohort
Prospective
Treatments tested in this trial
blood gas analysis
Other intervention1. Airway pressure (P plateau, Ppeak) values are taken from the anesthesia device data, 2. BIS (from routine BIS monitoring) 3. Temperature (routinely from pharyngeal temperature probe), 4. Oxygen saturation (routinely from the patient monitor) 5. End-tidal CO₂, 6. inspiratory O₂ concentration, 7. Inspiratory CO2 concentration, 8. inspiratory and expiratory desflurane concentrations, 9. tidal volume, 10. MAC is routinely obtained from anesthesia device data. 11. Blood Gas Analysis (COHgb, Ph, PO2, PCO2, SaO2, HCO3, Base deficit, glucose, lactate)
Treatment groups
Trial outcomes
Primary outcomes
inspiratory O2 concentration
inspiratory O2 concentration is measured from anesthesia machine monitor
partial oxygen pressure
PO2 from blood gas analysis
Secondary outcomes
desflurane consumption
desflurane consumption
changes in liver and kidney function tests from the preoperative values to 48 hours postoperative
to determine the changes in serum aspartate aminotransferase (AST), alanine aminotransferase (ALT), blood urea nitrogen (BUN), and creatinine from the preoperative values to 48 hours postoperative
Sponsors and contacts
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