Comparison of Motor Relearning Program and Electric Muscle Stimulation in Subacute Stroke Patients

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-65
SponsorMontiha Azeem

About this trial

Stroke is one of the leading causes of long-term disability worldwide, with upper limb motor impairment being a common consequence that limits independence in activities of daily living. The Motor Relearning Program (MRP) is a task-oriented rehabilitation approach designed to improve motor recovery through repetitive functional practice. Electrical Muscle Stimulation (EMS) may further enhance muscle activation and facilitate motor recovery when combined with conventional rehabilitation.

The purpose of this single-blinded randomized controlled trial is to compare the effectiveness of the Motor Relearning Program combined with Electrical Muscle Stimulation versus the Motor Relearning Program alone in improving upper limb function in individuals with subacute stroke. Thirty-six eligible participants with subacute stroke will be randomly allocated into two groups. Group A will receive MRP together with EMS, while Group B will receive the same MRP without EMS. Both groups will undergo treatment for 1 hour per day, 5 days per week, for 6 weeks.

Upper limb motor recovery and muscle tone will be evaluated at baseline and after the intervention using the Upper Extremity Fugl-Meyer Assessment (UEFMA), Modified Ashworth Scale (MAS), and Motor Evaluation Scale for Upper Extremity in Stroke (MESUPES). The findings of this study may help determine whether adding EMS to a structured Motor Relearning Program provides greater improvements in upper limb function than MRP alone in individuals with subacute stroke.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age 40-65 years

Both male and female

Sub acute stroke patients diagnosed by neurologist

Motor assessment scale score 2-3

Disqualifiers

Patients with Mini Mental State Examination <23

Cognitive disorders and perceptual disorders

Any musculoskeletal disorders

Severe cardiac diseases

Trial design

Design model

Parallel

Treatments tested in this trial

  • Motor Relearning Program

    Behavioral

    Participants will receive a structured Motor Relearning Program consisting of repetitive task-oriented upper limb activities, including reaching, grasping, object manipulation, lifting, puzzle arrangement, and functional daily living tasks. Therapy will be provided for 1 hour per session, 5 days per week, for 6 weeks, with progressive increases in task difficulty according to participant performance.

  • Electrical Muscle Stimulation

    Device

    Electrical Muscle Stimulation will be applied to the affected upper limb muscles, including the deltoid, biceps brachii, triceps brachii, wrist flexors and extensors, and finger flexors and extensors, using surface electrodes for 10 minutes during each treatment session. Stimulation intensity will be adjusted to produce visible, pain-free muscle contractions according to participant tolerance. EMS will be administered in combination with the Motor Relearning Program, 5 days per week for 6 weeks.

Treatment groups

36 Participants
are divided into 2 treatment groups
Group A: group A Motor Relearning Program + Electrical Muscle StimulationExperimental treatment 1 intervention
Group B: group B Motor Relearning ProgramActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Upper Extremity Fugl-Meyer Assessment (UEFMA)

The UEFMA will be used to assess upper limb motor recovery following the intervention. Scores obtained at baseline and after the 6-week intervention will be compared between the two study groups to evaluate changes in upper extremity motor function.

Time frame
Baseline and Week 6

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Montiha Azeem

Lead sponsor

University of Lahore

Sponsor institution