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Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoarthritis. (KOA PRP ACS)

ConditionsKnee Arthritis OsteoarthritisPlatelet Rich Plasma InjectionConditioned Serum
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age40-80
SponsorPamukkale University

About this trial

The effects of single dose injection of platelet rich plasma or conditioned serum in the knee joint in patients with knee osteoarthritis will be compared

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Diagnosis of knee osteoarthritis according to ACR criteria at least 6 months ago.

Being between grade 1-2 according to the Kellgren-Lawrence radiological classification.

Not having had PRP injection in the last year.

Knee pain ≥ 5 according to the visual pain scale.

Disqualifiers

Those with significant neurological or cardiovascular disorders.

Those with active thrombovascular disease.

Those with joint or skin infections.

Those who have recently had an infectious disease.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Autologous Platelet-Rich Plasma (PRP)

    Drug

    Autologous Platelet-Rich Plasma (PRP) will be injected intra-articularly in patients with knee osteoarthritis

  • Conditioned serum (CS)

    Drug

    Autologous conditionedserum (CS) will be injected intra-articularly in patients with knee osteoarthritis

Treatment groups

60 Participants
are divided into 2 treatment groups
Group A: PRP groupExperimental treatment 1 intervention
Group B: conditioned serum groupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Visual pain scale score

Visual pain scale score (min 0-max 10), higher scores indicate better results

Time frame
Visual pain scale score (min 0-max 10) will be measured at the beginning ofthe study, 1 week, 1month and 3 months after the injection.

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Pamukkale University

Lead sponsor

Source ClinicalTrials.gov
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