Comparison of Preoperative Frailty Assessment Tools
Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age70+
SponsorUniversitätsklinikum Hamburg-Eppendorf
About this trial
Frailty is a significant risk factor for postoperative complications and functional decline. Preoperative assessment of frailty is therefore recommended in all older adults. However, despite the availability of many frailty tools, few have been tested in the preoperative setting and there is little comparison of their predictive value in identifying patients at risk. The aim of this study is to investigate which of the following instruments for determining frailty has the highest predictive power with regard to the occurrence of postoperative complications: Risk Analysis Index, Clinical Frailty Scale, the Groningen Frailty Indicator, the Edmonton Frail Scale and the LUCAS-FI. The aim of this research project is to identify a suitable frailty instrument for preoperative risk stratification of older patients during the premedication visit.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
70 years and older
scheduled surgery
estimated time of surgery 120 Minutes or more
Disqualifiers
insufficient German language skills (for cognitive testing)
mental retardation
relevant psychiatric disorder (not allowing for cognitive testing)
Trial population
Patients of the Medical University Centre Hamburg, Germany
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Assessment of frailty using multiple tools
Other interventionThis is an observational study without any intervention. Frailty is assessed using multiple tools and postoperative outcome is compared.
Treatment groups
584 Participants
are divided into 1 treatment groupGroup A: Older patients1 intervention
Trial outcomes
Primary outcomes
1
Complications in the first 30 days after surgery
Measured by Clavien-Dindo classification
Time frame
30 daysSecondary outcomes
1
Functional state (activities of daily living)
Measured using WHO Disability Assessment Schedule 2.0
Time frame
one, three and six months after surgery2
Postoperative Quality of Recovery
Measured by Quality-of-Recovery-15 questionnaire
Time frame
postoperative day 23
Muscle loss during hospitalisation
measured by bioimpedance prior to admission and before discharge from hospital
Time frame
From date of enrollment, up to 4 weeks after surgery4
Postoperative delirium
Measured by 3D-Confusion Assessment Method
Time frame
postoperative day 1 to 5Sponsors and contacts
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Source ClinicalTrials.gov