Comparison of Short- and Long-term Outcomes Between Robotic and Laparoscopic Hemicolectomy of Right Colon Cancer : A Multicenter Propensity Score Matching Analysis

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorThe First Affiliated Hospital of Nanchang University

About this trial

This is a retrospective, multicenter cohort study to compare short- and long-term outcomes between robotic and laparoscopic hemicolectomy of right colon cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

1.Underwent radical right hemicolectomy by Da Vinci robotic or laparoscopic surgery 2.Postoperative pathology confirmed right colon adenocarcinoma (pT2-T4aNxM0; including cecal adenocarcinoma, ascending colon adenocarcinoma, hepatic flexure colon adenocarcinoma, and proximal transverse colon adenocarcinoma) 3.Complete clinical data and pathological results available

Disqualifiers

1.Received neoadjuvant therapy prior to surgery 2.History of other malignancies in the past 5 years (except cured cervical carcinoma in situ, basal cell carcinoma, or squamous cell carcinoma of the skin) 3.Distant metastases (e.g., liver, lung) or extensive abdominal/pelvic metastases confirmed by contrast-enhanced CT, PET-CT, or intraoperative exploration 4.Comorbid neurological/psychiatric disorders impairing ability to express informed consent 5.Poor systemic condition with contraindications to general anesthesia 6.Severe obesity (BMI >35 kg/m²) 7.Severe widespread abdominal adhesions precluding safe pneumoperitoneum establishment 8.Emergency surgery due to tumor perforation or obstruction 9.Refusal to provide informed consent

Trial population

The procedures were performed by 16 surgeons from 16 participating centers. Both primary surgeons and assistants completed standardized training in robotic and laparoscopic surgical techniques and obtained certification. Each center performs over 100 robotic- or laparoscopic-assisted radical right hemicolectomies annually. Primary surgeons had performed at least 50 cases of both robotic and laparoscopic-assisted radical right hemicolectomy.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

4,000 Participants
are grouped into 2 trial groups
Group A: R Group
Group B: L Group

Trial outcomes

Primary outcomes

1

3-year overall survival (OS) rate and 3-year disease-free survival (DFS) rate

Time frame
(OS)From post-operation until death or the 3-year study endpoint (DFS)From post-operation to tumor recurrence or the 3-year study endpoint

Secondary outcomes

1

Operative time

Time frame
Periprocedural
2

Intraoperative blood loss

Time frame
Periprocedural
3

Time to first flatus/bowel movement

Time frame
Periprocedural
4

Time to liquid diet initiation

Time frame
Periprocedural

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

The First Affiliated Hospital of Nanchang University

Lead sponsor

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Collaborator

Fudan University

Collaborator

The Second Affiliated Hospital of Harbin Medical University

Collaborator

Three Gorges Hospital of Chongqing University

Collaborator

The Affiliated Hospital of Qingdao University

Collaborator

The First Affiliated Hospital of Zhengzhou University

Collaborator

Tianjin Third Central Hospital

Collaborator

Shandong University Second Hospital

Collaborator

Nanfang Hospital, Southern Medical University

Collaborator

Huadong Hospital

Collaborator

Second Affiliated Hospital, School of Medicine, Zhejiang University

Collaborator

Second Xiangya Hospital of Central South University

Collaborator

Jiangxi Provincial People's Hopital

Collaborator

Pingxiang People 's Hospital

Collaborator

Ganzhou City People's Hospital

Collaborator

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