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Comparison of the Analgesic Effects of TFPB in Renal Transplantation Surgery

ConditionsRenal TransplantationPeripheral Nerve BlockPain Management
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorAnkara Etlik City Hospital

About this trial

Renal transplantation is a major surgical procedure associated with significant postoperative pain, particularly due to lower abdominal incision, deep tissue dissection, and extensive surgical manipulation. Effective postoperative pain control is therefore of great importance in this patient population, as inadequate analgesia may impair early mobilization, delay recovery, increase opioid consumption, and contribute to opioid-related adverse effects. In addition, optimal analgesic management may improve patient comfort and support enhanced postoperative outcomes.

Nerve blocks reduces opioid consumption in the postoperative period by providing better pain control and therefore has advantages such as fewer side effects and less risk of pulmonary and cardiac complications.

In this study; it was aimed to compare the analgesic effectiveness of transversalis fascia plane block in the postoperative period in patients who underwent renal transplantation.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18-65 years

American Society of Anesthesiologists (ASA) score III

Body Mass Index (BMI) between 18-30 kg/m2

Disqualifiers

Patients under 18 and over 65 years of age

Patients with an ASA score other than III

Patients with a history of bleeding diathesis

BMI below 18 or above 30 kg/m2

Trial design

Design model

Parallel

Treatments tested in this trial

  • Transversalis Fascia Plane Block Group

    Procedure/Surgery

    This procedure will be performed unilaterally on the surgical side. 30 ml of 0.25% bupivacaine will be injected for ultrasound-guided transversalis fascia plane block application. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.

  • Control Group

    Procedure/Surgery

    No peripheral nerve block will be performed. The standard intraoperative analgesic regimen will consist of intravenous tramadol (1 mg/kg) administered both before the incision and at the end of the procedure, with intravenous paracetamol (10 mg/kg) given exclusively at the end of the surgery.

Treatment groups

50 Participants
are divided into 2 treatment groups
Group A: Transversalis Fascia Plane Block GroupActive comparator 1 intervention
Group B: Control GroupActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Pain Scores

Pain will be assessed at rest and while coughing using the visual analog scale on a scale from 0 (no pain) to 10 (worst pain). Pain assessment will be done at 1st, 2nd, 4th, 12th, and 24th hours after surgery

Time frame
On the operation day

Secondary outcomes

1

Intraoperative opioid consumption

Remifentanil consumption for intraoperative period will be recorded

Time frame
Intraoperative period
2

Postoperative Opioid Consumption

Opioid consumption for 24 hours will be recorded

Time frame
On the operation day

Other outcomes

Sponsors and contacts

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Ankara Etlik City Hospital

Lead sponsor

Source ClinicalTrials.gov
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