Comparison of the Sensibility of Swept Source Optical Coherence Tomography Devices in the Detection of Neovascularisation in Large Pigment Epithelium Detachments

ConditionAMD - Age-Related Macular Degeneration

Trial statusNot yet recruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

AgeNot listed

SponsorUniversity of Trieste

About this trial

The goal of this observational study is to compare swept source optical coherence tomography devices ability to detect macular neovascularisation when there is a large pigment epithelium detachment higher than 250 microns

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients treated for neovascular age related macular degeneration (AMD)

Presence of a pigmentary epithelium detachment higher than 250 microns measured on structural optical coherence tomography (OCT)

Disqualifiers

Poor image quality or signal strength

Undefined retina layers

Trial population

Patients treated for neovascular age related macular degeneration (AMD)

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Optical Coherence Tomography Angiography (OCT-A)
Diagnostic test
Two Optical Coherence Tomography Angiography swept source devices are compared for the detection of large pigment epithelium detachments in age related macular degeneration. The sensitivity of the devices is compared in both the automatic segmentation done by the device and the manual segmentation done by a retina specialist.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

Sensitivity of the detection of neovascularisation in large pigment epithelium detachment by swept source optical coherence tomography devices

The optical coherence tomography angiography devices are known to have a difficult time detecting neovascularisation in the cases of large pigment epithelium detachments (PED), because of the many layers and the distance the OCT signal has to cross. The automatic retina segmentation (done by the device of the different retina layers plays a big role in this detection. It's also disturbed by the height of the PED. This study aims to compare the sensitivity of two swept source OCT devices available in the market : Bmizar, Towardpi and Plexelite, Zeiss. After the exam image acquisition, a retina specialist will try to make a manual segmentation of the retina analysed to help the detection of macular neovascularisation that would have been missed in the "normal" automatic segmentation done by the device.

Time frame

Day 1

Sponsors and contacts

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University of Trieste

Lead sponsor

Source ClinicalTrials.gov

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