Health TrialsbyHealthPanel

Comprehensive Swallowing Rehabilitation in Patients With MSA

ConditionMultiple System Atrophy
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age19+
SponsorSeoul National University Hospital

About this trial

The purpose of this study is to investigate the effect of comprehensive swallowing rehabilitation in patients with multiple system atrophy.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age >19 years

Clinically diagnosed with MSA according to the guidelines of the 2nd consensus of the Gilman criteria

Clinically diagnosed to have dysphagia by a physiatrist

Two or more points on the Penetration-aspiration scale (PAS) from the Videofluoroscopic swallowing study (VFSS) conducted within 3 months

Disqualifiers

Moderate to severe cognitive dysfunction with Mini-mental State Examination score < 19

Comorbidities or structural abnormalities that may affect swallowing function

Other comorbidities that make it difficult to participate in the study

Trial design

Design model

Parallel

Treatments tested in this trial

  • Comprehensive swallowing rehabilitation

    Other intervention

    The treatment time per session is 30 minutes. Total 12 sessions are provided for 6 weeks.

  • Swallowing education

    Other intervention

    The education is 30 minutes. Total 1 session is provided immediately after baseline evaluation.

Treatment groups

24 Participants
are divided into 2 treatment groups
Group A: Comprehensive swallowing rehabilitationExperimental treatment 1 intervention
Group B: Swallowing educationActive comparator 1 intervention

Trial outcomes

Primary outcomes

1

Penetration-Aspiration Scale

Time frame
at 6 weeks
2

Videofluoroscopic dysphagia scale

Time frame
at 6 weeks

Secondary outcomes

1

Penetration-Aspiration Scale

Time frame
at 12 weeks
2

Videofluoroscopic dysphagia scale

Time frame
at 12 weeks
3

Peak Cough Flow

Time frame
at 6 weeks, at 12 weeks
4

Maximal Inspiratory Pressure

Time frame
at 6 weeks, at 12 weeks

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Seoul National University Hospital

Lead sponsor

Source ClinicalTrials.gov
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