Conceptualisation of a Network Approach to Complete the Classification of Eating Disorders With the Aim of Better Personalising Their Management

Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age15-65
SponsorUniversity Hospital, Montpellier

About this trial

Eating disorders (EDBs) are mental disorders with a great impact on the lives of individuals as well as a great cost imposed on society. The treatments currently available rely on different forms of psychotherapies with an unsatisfactory response rate as well as a considerable relapse rate . One of the reasons underlying the low success of available therapeutic modalities would be the heterogeneity of the clinical presentation of EDs, making their classification and the personalization of their treatment more difficult.The investigators hypothesize that a secondarily dimensional classification approach (respecting the categorical classification currently in use) of EDs based on the different dimensions disturbed in these disorders as well as in their comorbidities, would better represent their nosographic reality, which could provide patients with more personalized and potentially more effective care.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient with an eating disorder according to DSM-V criteria

Patient aged from 15 to 65 years

Patient who performs the day-hospital evaluation

Patient affiliated to a French social security system

Disqualifiers

Patient in an unstable somatic state (eg severe metabolic disorder making impossible or unreliable neuropsychological assessments)

Patient's refusal to participate

Patient protected by law (guardianship or curatorship)*

Pregnant or nursing women. A dosage of βHCG will be performed to ensure the absence of pregnancy

Trial design

Design model

Single group

Treatments tested in this trial

  • Ambulatory cares in a day-hospital (Lapeyronie, Montpellier) specialized in the evaluation of eating disorders.

    Behavioral

    All patients assessed in the day-hospital will permormed the same evaluation : * Blood sampling * Calorimetry * Osteodensotometry * Psychiatric assement * Endocrinologic assessment * Dietetic assessment * Neuropsychological assessment * Self-questionnaires With the patient agreement, a biological collection will be constituted. The objective is the subsequent study of biological factors involved in eating disorders (in particular genetic factors)

Treatment groups

840 Participants
are divided into 1 treatment group
Group A: ParticipantsOther 1 intervention

Trial outcomes

Primary outcomes

1

Eating Disorders Inventory (EDI-2)

self-questionnaire of 91 items aimed at evaluating attitudes and behaviors related to food and allowing the identification of 11 dimensions: search for thinness, bulimia, body dissatisfaction, inefficiency, perfectionism, interpersonal distrust, interoceptive awareness, fear of maturity , asceticism, impulse control, social insecurity. The higher the subscore, the more severely impaired the dimension concerned is.

Time frame
Baseline
2

Eating Disorder Examination Questionnaire (EDE-Q)

Self-reported version of the gold-standard clinical interview for ED assessing the intensity of eating symptoms over the last 28 days. A total score as well as 4 sub-scores (restriction, diet, weight, shape) varying from 0 to 6 are thus obtained.

Time frame
Baseline

Secondary outcomes

1

Symptomatic dimensions of Eating Disorder Examination Questionnaire (EDEQ)

Self-reported version of the gold-standard clinical interview for ED assessing the intensity of eating symptoms over the last 28 days. A total score as well as 4 sub-scores (restriction, diet, weight, shape) varying from 0 to 6 are thus obtained.

Time frame
baseline
2

Body Shape Questionnaire (BSAQ-34)

self-questionnaire of 34 items assessing body dissatisfaction and in particular four dimensions: avoidance and social shame of body exposure, body dissatisfaction with the lower parts of the body, use of laxatives and vomiting to reduce body dissatisfaction, maladaptive cognitions and behaviors in order to control weight. The total score ranges from 0 to 204. A score below 80 indicates no excessive body concerns, a score between 80 and 100 indicates mild concerns, between 111 and 140 moderate concerns, and a score above 140 indicates significant concerns

Time frame
baseline
3

Yale Food Addiction Scale (YFAS)

35-item Likert-type self-questionnaire assessing the difficulty or not in controlling the quantity of food one eats over the past 12 months, using an 8-point scale from "never" to "all days ". This questionnaire assesses clinical distress based on the DSM-5 diagnostic criteria for substance use disorders. Presenting clinically significant suffering and at least 2 diagnostic criteria suggest a food addiction.

Time frame
baseline
4

Sociocultural Attitudes Towards Appearance Scale (SATAQ-4)

multidimensional self-questionnaire of 22 items rated from 1 (completely disagree) to 5 (completely agree) aimed at assessing the sociocultural influence of the media on appearance. It includes four subscales: pressures, information, internalization relating to athletes and general internalization. The higher the score, the stronger the influence.

Time frame
baseline

Other outcomes

Locations

This trial has no locations.

Sponsors and contacts

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