Conceptualizing Borderline Personality Disorder as a Relationship Use Disorder

Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-45
SponsorUniversity Hospital, Montpellier

About this trial

This study aims to explore a novel conceptualization of Borderline Personality Disorder (BPD) as a "Relationship Use Disorder." The research proposes that BPD shares key features with behavioral addictions, specifically addiction to interpersonal relationships. The study builds upon previous findings suggesting that individuals with BPD experience intense emotional dysregulation, including negative self-perception, shame, and a compulsive need for external validation. This addiction to relationships, much like substance use disorders, is thought to contribute significantly to the difficulties faced by these individuals, including interpersonal conflicts, self-destructive behaviors, and emotional instability.

The study seeks to demonstrate that the relational difficulties central to BPD meet the diagnostic criteria for addiction as defined by the DSM-5. It will also explore how these relational struggles are mediated by dysfunctional self-perception and whether they are linked to behaviors such as compulsive sexual behaviors (CSBD) or suicidal tendencies. Additionally, the research will investigate the relationship between addiction to relationships and neurobiological factors, including endorphin levels, in individuals with BPD compared to those with bipolar disorder and healthy controls. The hypothesis is that individuals with BPD will exhibit higher levels of relationship addiction, with this addiction being tied to their perception of self-worth and emotional experiences in relationships.

This innovative approach aims to refine the understanding of BPD, reduce stigma, and improve treatment strategies by providing scientific evidence supporting the conceptualization of BPD as a "Relationship Use Disorder."

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

General : aged 18-45

Borderline personality disorder (BPD)assessed by SCID, without bipolar disorder

Bipolar disorder (assessed by SCID), without BPD (evaluated by SCID)

Healthy controls with no psychiatric disorders (screened by SCID).

Disqualifiers

Psychotic disorders (evaluated by SCID)

lack of informed consent

Not affiliated with social security

Under judicial or administrative confinement or involuntary hospitalization

Trial design

Design model

Parallel

Treatments tested in this trial

  • Relationship-use questionnaire

    Other intervention

    Questionnaire adapted from the 'Substance Use Disorders' section of the DSM-5: Disorder related to the use of close relationships

Treatment groups

194 Participants
are divided into 3 treatment groups
Group A: Patients with borderline personalityExperimental treatment 1 intervention
Group B: Patients with bipolar disorderExperimental treatment 1 intervention
Group C: Healthy controlsExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Relational Addiction

Using the experimental relationship-use questionnaire based on the DSM-5 Substance Use Disorder items among patients with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD, and healthy controls.

Time frame
Measured at baseline

Secondary outcomes

1

Function Acquisition Speed Test (FAST)

Administer the Function Acquisition Speed Test (FAST) to measure how quickly individuals learn associations between stimuli and responses, focusing on emotional biases related to self (e.g., feelings of unworthiness, ridicule) and others (e.g., dependency, validation). The aim is to assess the intensity of emotional biases in BPD patients compared to BD patients and healthy controls.

Time frame
Measured at baseline
2

Visual Analogue Scale (VAS) for Perceived Alignment with BPD

After viewing an educational video explaining Borderline Personality Disorder (BPD) as relational addiction, assess how participants perceive the alignment of their personal experiences with BPD traits, using a Visual Analogue Scale (VAS) ranging from 0 to 10.

Time frame
Measured at baseline
3

Love Addiction Inventory (LAI)

Using the Love Addiction Inventory (LAI), a 24-item self-report scale, to measure symptoms of love addiction. Participants rate their responses on a 5-point Likert scale, with higher scores indicating greater levels of love addiction symptoms, among patients with Borderline Personality Disorder (BPD) without Bipolar Disorder (BD), those with BD without BPD.

Time frame
Measured at baseline
4

Beta-Endorphin Levels

valuate the correlation between beta-endorphin levels and the dimension of relational addiction among patients with BPD, BD, and healthy controls

Time frame
Measured at baseline

Other outcomes

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