Conduction System Vs Surgical Left Ventricular Epicardial Pacing For Coronary Sinus Lead Failure

ConditionHeart Failure With Reduced Ejection Fraction

Trial statusRecruiting

Trial phaseNot listed

Trial typeObservational

Biological sexAll

Age18+

SponsorKansas City Heart Rhythm Research Foundation

About this trial

This a single-center, retrospective, observational study of patients that undergo coronary sinus(CS) lead revision, comparing epicardial lead placement to coronary sinus pacing(CSP) in those that had lead failure.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

All patients older than 18 years of age

Patients with HFrEF that underwent BVP-CRT

Experienced CS lead failure, whether initial or recurrent, subsequently replaced with transthoracic epicardial lead placement or CSP

Underwent Medtronic, Boston Scientific, or Abbott lead placement

Disqualifiers

Patients younger than 18 years of age

Transthoracic epicardial lead placement or CSP performed as the initial approach or for other reasons than lead replacement

Those for which CRT no longer provides symptom relief or mortality benefit.

Trial population

Adults who underwent CS lead revision, comparing epicardial lead placement to CSP in those that had lead failure.

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Coronary Sinus Lead Revision
Other intervention
Coronary Sinus Lead Revision

Treatment groups

100 Participants

are divided into 2 treatment groups

Group A: Conduction System Pacing1 intervention

Group B: Epicardial Lead Placement1 intervention

Trial outcomes

Primary outcomes

Need for lead revision

Compare the need for lead revision between conduction system pacing (CSP) and transthoracic left ventricular (LV) epicardial pacing approach

Time frame

Procedure Day

Secondary outcomes

Electrocardiography characteristics - QRS Interval

Compare electrocardiography characteristics - QRS Interval measured in seconds between conduction system pacing (CSP) and transthoracic left ventricular (LV) epicardial pacing approach

Time frame

Procedure Day

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Kansas City Heart Rhythm Research Foundation

Lead sponsor

Source ClinicalTrials.gov

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