This study aimed to evaluate the diagnostic yield and safety of confocal laser endomicroscopy and ultrasound-guided pleural biopsy in diagnosing patients with unknown pleural effusion.
Adult patients with exudative pleural effusion of unknown origin
Patients with negative pleural fluid cytology results
Patients diagnosed with a probable malignant pleural effusion but without a definite diagnosis and requiring further pathological evaluation
Patients who are fully informed of the purpose and method of the study, agree to participate in the study, and sign an informed consent form
Inability or refusal to undergo UGBx
Patients with any contraindications for pleural biopsy
Parallel
Confocoal laser endomicroscopy-assisted ultrasound-guided pleural biopsy
Procedure/SurgeryUsing the probe-based confocal laser endomicroscopy to detect the pleural, and ensure the biopsy location. Then, use the pleural biopsy tool to complete the pleural biopsy. The whole procession will under the ultrasound guidance.
Ultrasound-guided pleural biopsy
Procedure/SurgeryUsing ultrasound to detect the biopsy site and perform pleural biopsy.
Diagnostic yield
The proportion of all individuals undergoing the diagnostic procedure under evaluation in whom a specific diagnosis is established based on the consensus definition.
Click on the lead sponsor to view all of their trials.
This trial is not recruiting at the moment. You can still explore other options:
