Conservative Management of Left Ventricular Assist Device Candidates

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18-80
SponsorTel-Aviv Sourasky Medical Center

About this trial

Left ventricular assist device (LVAD) candidates will be comprehensively evaluated at our center, including clinical evaluation, echocardiography, right heart catheterization, cardiopulmonary exercise test and laboratory exams. following this evaluation, patients will be treated with inotropes, diuretics, uptitrated neurohormonal therapy. vitamin and iron deficiencies will be corrected and the patients will be referred for coronary interventions and cardiac resynchronization therapy appropriately. The need for LVAD implantation will be reevaluated according to the patient's clinical condition, echocardiography and laboratory findings.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

None

Disqualifiers

None

Trial population

Advanced symptomatic heart failure patients with reduced ejection fraction in whom a left ventricular assist device implantation is planned.

Trial design

Design model

Case-only

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

No trial groups listed

Trial outcomes

Primary outcomes

1

New York Heart Association (NYHA) Class

improvement in NYHA class

Time frame
3 months

Secondary outcomes

1

Maximal oxygen consumption (VO2)

improvement in VO2

Time frame
6 months
2

natriuretic peptide levels

reduction in brain natriuretic peptide levels

Time frame
3 months
3

left ventricular size

reduction in left ventricular end diastolic diameter

Time frame
6 months

Other outcomes

Sponsors and contacts

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