Constitution of a Biobank for Studies Related to Organ Transplantation (Lyon Centaure Biocollection)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorHospices Civils de Lyon

About this trial

This study aims to constitute a collection of biological materials from in transplant patients and to provide biological materials from transplanted patients in order :

i) validate new theory on the cause of allograft loss, ii) develop innovative biomarker for rejection and other transplantation-related conditions (such as BK virus nephropathy, Post-transplant lymphoproliferative disorder ( PTLD) ...)

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Male or Female patient ≥18 years old

Recipient of an organ transplant

Written informed consent

Disqualifiers

Non-affiliation to a social security system.

Subjects deprived of liberties

Pregnant or breastfeeding woman

Trial population

All adult patients that received a solid organ transplant at the transplantation department of Lyon University Hospital

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

  • Biobank

    Other intervention

    For each patient included in the study the following samples will be collected at the indicated time points after transplantation: * Serum samples and plasma sample: Day1, Month 1, Month 3, Month 6, Month 12, month 60, month 120 and at the time of each allograft biopsy. * Urines samples: Month 3 and Month 12 and at the time of each allograft biopsy. * Peripheral Blood Mononuclear Cell (PBMC): for each organ allograft biopsy. * Allograft biopsies: systematically at Month 3, and Month 12, and for cause in case of allograft dysfunction.

Treatment groups

No treatment groups listed

Trial outcomes

Primary outcomes

1

the biological samples

The goal of this study is to provide biological materials from transplanted patients

Time frame
At inclusion
2

Change Biological Samples

The goal of this study is to provide biological materials from transplanted patients

Time frame
Month 1
3

Change Biological Samples

The goal of this study is to provide biological materials from transplanted patients

Time frame
Month 3
4

Change Biological Samples

The goal of this study is to provide biological materials from transplanted patients

Time frame
Month 6

Secondary outcomes

Other outcomes

Sponsors and contacts

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