Cardiovascular disease (CVD) is the leading cause of global morbidity and mortality, with its prevalence increasing significantly from 1990 to 2019. Establishing a comprehensive cardiac surgery database is crucial for exploring perioperative prognostic factors and improving clinical outcomes.
This muti-center, prospective observational study aims to construct a prospective cohort database for perioperative cardiac surgery. We plan to enroll adult patients who undergo cardiac surgery with cardiopulmonary bypass at the Second Affiliated Hospital of Zhejiang University and other hospitals from May 1, 2026 to December 31, 2031. Multi-dimensional perioperative data, including laboratory tests, hemodynamics, intraoperative echocardiography, and perioperative medications, will be collected and integrated, along with epidemiological data, clinical diagnosis and treatment information, multimodal data, and follow-up outcomes. An interconnected big data sharing platform will also be built.
This database will provide a valuable resource for multi-level researches such as perioperative risk assessment, individualized prevention, precise diagnosis and treatment, and therapeutic efficacy monitoring. It will also help optimize surgical and perioperative management, improve the quality of cardiac surgery, and provide evidence for the refinement of China's healthcare system, ultimately enhancing perioperative safety and rehabilitation efficiency of patients.
Patients undergoing cardiac surgery from May 1, 2026 to December 31, 2031
Refusal to provide informed consent
Patients undergoing cardiac surgery from May 1, 2026 to December 31, 2031
Cohort
Prospective
Cardiac surgey
Procedure/SurgeryCardiac surgey
Incidence of major adverse cardiac and cerebrovascular events (MACCE)
Myocardial infarction; New-onset stroke: new irreversible neurological impairment confirmed by radiological examination or autopsy showing a new cerebral lesion; Death
Incidence of Perioperative Transfusion of Allogeneic Blood Products
Allogeneic red blood cells, plasma, platelets, and blood coagulation factors
Amount of Allogeneic Blood Products Transfused During the Perioperative Period
Allogeneic red blood cells, plasma, platelets, and blood coagulation factors
Incidence of perioperative myocardial infarction
Myocardial infarction
Incidence of New-onset stroke
New-onset stroke: new irreversible neurological impairment confirmed by radiological examination or autopsy showing a new cerebral lesion
Incidence of death
death
Incidence of acute kidney injury
acute kidney injury was defined by guidelines of kindey disease：improving global outcomes（KIDGO）
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