Contrast-enhanced CT-based Deep Learning Model for Preoperative Prediction of Disease-free Survival (DFS) in Localized Clear Cell Renal Cell Carcinoma (ccRCC)

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
AgeNot listed
SponsorMingzhao Xiao

About this trial

This study aims to preoperatively predict DFS of patients with localised ccRCC using a deep learning prognostic model based on enhanced contrast CT images, validate it's predictive ability in multicentre data and compare it's predictive ability with traditional models.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

underwent partial/radical nephrectomies

histologically diagnosed as ccRCC

with complete clinical data and preoperative CT image data

Disqualifiers

with incomplete clinic-pathological data

lack of preoperative contrast-enhanced CT images or the image quality was unsuitable for analysis

who received pre-surgery neoadjuvant or adjuvant therapies

with multiple renal tumors or/and had synchronous metastasis

Trial population

Patients admitted to urology departments at participating medical centres

Trial design

Design model

Cohort

Time perspective

Retrospective

Treatments tested in this trial

Not listed

Trial groups

800 Participants
are grouped into 2 trial groups
Group A: Non-recurrence group
Group B: Recurrence group

Trial outcomes

Primary outcomes

1

disease-free survival (DFS)

the interval from the date of surgery to disease recurrence, all-cause mortality or the last visit

Time frame
recruitment occurred between June 2013 and March 2020

Secondary outcomes

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

Mingzhao Xiao

Lead sponsor

First Affiliated Hospital of Chongqing Medical University

Sponsor institution