Controlling Locomotion Over Continuously Varying Activities for Agile Powered Prosthetic Legs
ConditionAmputation
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorUniversity of Michigan
About this trial
The overall goal of this project is to model human joint biomechanics over continuously-varying locomotion to enable adaptive control of powered above-knee prostheses. The central hypothesis of this project is that variable joint impedance can be parameterized by a continuous model based on measurable quantities called phase and task variables. This project will use machine learning to identify variable impedance functions from able-bodied data including joint perturbation responses across the phase/task space to bias the solution toward biological values.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Aged between 18 to 65 years
Disqualifiers
Pregnant (self-report)
Any significant neuromuscular or musculoskeletal disorder that would interfere with the study
Unable to walk for 20 minutes
History of any cardiovascular, vestibular, or visual diseases and/or impairments that may interfere with the study
Trial design
Design model
Single group
Treatments tested in this trial
Powered prosthesis
DeviceA powered prosthesis will be used to restore normative leg biomechanics to above-knee amputee participants during different activities of daily life.
Treatment groups
40 Participants
are divided into 1 treatment groupGroup A: ProsthesisExperimental treatment 1 intervention
Trial outcomes
Primary outcomes
1
Joint work
Mechanical work at the prosthetic knee and ankle will be assessed for participants using the powered prosthesis in A1.3 and A2.3, with comparisons to able-bodied averages. Joint work will be calculated by multiplying the joint's commanded torque by its measured velocity, resulting in units of Joules.
Time frame
1 day2
Tuning time
The time for a prosthetist to configure the powered prosthesis for above-knee amputee participants will be assessed in A3.1 and A3.3.
Time frame
1 day3
Endurance test time
The time to complete multiple cycles through an ambulation circuit will be recorded with above-knee amputee participants' take-home prosthesis and a powered prosthesis. The ambulation circuit comprises, sit-to-stand, walking, stair ascent/descent, ramp descent/ascent, and stand-to-sit.
Time frame
1 daySecondary outcomes
1
Inter-leg symmetry
Kinematic and kinetic symmetry will be assessed between the sound side and prosthetic side of participants using the powered prosthesis in A1.3 and A2.3, with comparisons to able-bodied averages. The units will be % difference between legs, where 0% indicates perfect symmetry.
Time frame
1 day2
Stance-swing time ratio
The stance-swing time ratio will be assessed for participants using the powered prosthesis in A1.3 and A2.3, with comparisons to able-bodied averages. The stance-swing time ratio for above-knee amputee participants will compared between their take-home prosthesis and a powered prosthesis in A3.3.
Time frame
1 day3
Step time symmetry
Step time symmetry (between sound and prosthetic side) of above-knee amputee participants will compared using their take-home prosthesis and a powered prosthesis in A3.3. The units will be % difference between legs, where 0% indicates perfect symmetry.
Time frame
1 day4
Step length symmetry
Step length symmetry (between sound and prosthetic side) of above-knee amputee participants will compared using their take-home prosthesis and a powered prosthesis in A3.3. The units will be % difference between legs, where 0% indicates perfect symmetry.
Time frame
1 daySponsors and contacts
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Source ClinicalTrials.gov