This study aims at assessing the correlation between trans esophageal pressure and related respiratory mechanics (including, among others, nasal pressure-Pnose) and non-invasive respiratory support failure in patients with acute hypoxic respiratory failure of different etiology (including COVID-19).
Age >18 years
Acute hypoxic respiratory failure (P/F < 200)
Acute pulmonary edema
Chest wall deformities
Immediate need for Mechanical Ventilation
Pregnancy
See inclusion criteria
Cohort
Prospective
Not listed
Esophageal pressure impact on non invasive respiratory support (NRS) failure
Correlation between esophageal pressure values within 24 hours from NRS start and NRS failure
Transpulmonary pressure impact on NRS failure
Correlation between transpulmonary pressure values within 24 hours from NRS start and NRS failure
Dynamic compliance impact on NRS failure
Correlation between dynamic compliance values within 24 hours from NRS start and NRS failure
Dynamic mechanical power impact on NRS failure
Correlation between dynamic mechanical power within 24 hours from NRS start and NRS failure
Correlation between nasal pressure (Pnose) and esophageal pressure
Correlation between nasal pressure (Pnose) and esophageal pressure
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