About this trial
This observational study investigates whether the daily measured trend of cardiac output as evaluated by indirect calorimetry correlates with the same evaluated by transthoracic echocardiography.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients that received cardiac surgery
Perioperative requirement of extracorporeal life support (ECLS)
Age ≥ 18 years
Informed consent
Disqualifiers
Pregnancy or breastfeeding
Relationship or dependency with the study sponsor
Expected survival less than 72 hours after screening
Trial population
Patients of a university hospital
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Correlation of t two methods of determining cardiac output (determined by transthoracic echocardiography and determined by indirect calorimetry
1. Transthoracic echocardiography.:For this purpose, the diameter of the left ventricular outflow tract (LVOT) is measured echocardiographically. Furthermore, the velocity-time integral (VTI) is determined echocardiographically as an approximation of the flow per heartbeat. If this VTI is multiplied by the cross section of the left ventricular outflow tract and the heart rate, the cardiac CO can be estimated. 2. Indirect calorimetry. This is calculated as follows: Cardiac CO = (Calorimetry-VO2/ECLS-VO2)\*ECLS Blood Flow. For this purpose, calorimetry VO2 is measured directly and ECLS VO2 is calculated using the avDO2 (ECLS O2 content of the arterial cannula minus venous cannula) multiplied by the ECLS blood flow. This shortens the ECLS blood flow. It remains: CO = calorimetry-VO2/avDO2-ECLS.
Sponsors and contacts
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