Correlation of Dry Eye Disease, Problematic Smartphone Use and Sleep Quality in Adolescents and Young Adults

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age14-35
SponsorWei XIA, PhD

About this trial

The goal of this observational study is to learn about the status quo and relationship of dry eye, problematic smartphone use, bedtime procrastination, and sleep in adolescents and young adults. The main questions it aims to answer are:

* Is there a positive correlation between problematic smartphone use and dry eye? * Is problematic smartphone use positively correlated with bedtime procrastination? * Is bedtime procrastination negatively correlated with sleep quality? * Is there a negative correlation between sleep quality and dry eye? * Is there a negative correlation between problematic smartphone use and sleep quality? * Is there a positive correlation between bedtime procrastination and dry eye? * Do bedtime procrastination and sleep quality serve as mediating factors in the relationship of problematic smartphone use and dry eye? Participants will be asked to complete several questionnaires and dry eye related examinations.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Adolescents and young adults aged 14 to 35 (including 14,25 years old) ;

Agree to participate in the studies

Disqualifiers

Unable to communicate normally;

With ocular surface diseases other than dry eye and autoimmune diseases;

Use drugs that may cause damage to the ocular surface, such as anti glaucoma drugs, antidepressants, sex hormones, chemotherapy drugs, etc.;

With a history of eye trauma or eye surgery;

Trial population

General adolescents and young adults between 14-35 years old

Trial design

Design model

Other

Time perspective

Cross-sectional

Treatments tested in this trial

Not listed

Trial groups

453 Participants
are grouped into 1 trial group
Group A: Investigation Team

Trial outcomes

Primary outcomes

1

Dry eye symptoms

Ocular Surface Disease Index scale with 12-item will be used to measure dry eye symptoms. The scale uses Likert 5 comments, with a total score ranging from 0 to 100. And the total score reaching or exceeding 13 points indicates that participants exhibit symptoms of dry eye.

Time frame
baseline
2

Problematic smartphone use

The 10-item Smartphone Addiction Scale Short Version will be used to measure the problematic smartphone use. The scale uses Likert 6 comments, with a total score ranging from 10 to 60. And higher scores indicate more severe problematic smartphone use.

Time frame
baseline
3

sleep quality

The Pittsburgh Sleep Quality Index scale is used to measure participants' sleep quality. The total score ranges from 0 to 21. Higher scores indicate lower quality of sleep.

Time frame
baseline
4

bedtime procrastination

There are 9 items in the Bedtime Procrastination Scale, which is used to measure participants' bedtime procrastination. The scale uses 5-point scale, with a total score ranging from 9 to 45. And higher scores indicate more severe procrastination before sleep.

Time frame
baseline

Secondary outcomes

1

Perceived level of stress

The 14-item Chinese Perceived Stress Scale will be used to measure the perceived level of stress among adolescents and young adults. The scale uses Likert 5 comments, with a total score ranging from 0 to 56. And higher scores indicate a greater pressure that individuals feel in their daily lives.

Time frame
baseline
2

non-invasive tear film break-up time

Non-invasive tear film break-up time is measured by Oculus Keratograph 5M. A cut-off value of less than or equal to 10 s has been reported to be indicative of DED.

Time frame
baseline

Other outcomes

1

Tear meniscus height

The Ocular Keratograph 5M was utilized to measure the tear meniscus height directly beneath three points: the center of the pupil, the nasal corneal limbus, and the temporal corneal limbus. The average of these three measurements was calculated to serve as the final data for tear meniscus height.

Time frame
baseline
2

Meibomian gland loss

The degree of Meibomian gland loss was scored according to the meiboscore (Grade 0: no dropout, Grade 1: dropout of 2/3 of lid area, Grade 2: dropout of 1/3-2/3 of lid area, Grade 3: dropout of \>2/3 of lid area).

Time frame
baseline
3

Lipid layer thickness (LLT) and blinking pattern

The LLT and blinking pattern were assessed using LipiView interferometer. The LLT information included the minimum, maximum, and average for 20 seconds. The blinking pattern was obtained by determining the total blinking and partial blinking rates in 20 seconds and then calculating the partial blinking/total blinking ratio.

Time frame
baseline

Sponsors and contacts

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Wei XIA, PhD

Lead sponsor

Sun Yat-sen University

Sponsor institution

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