Correlation of Oxygenation and Saturation Indices in One-Lung Ventilation

Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorAnkara Ataturk Sanatorium Training and Research Hospital

About this trial

One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics. Traditional oxygenation indices require arterial blood gas analysis and do not fully reflect the mechanical stress applied to the lungs.

This prospective observational study aims to evaluate the correlation between oxygenation indices and oxygen saturation indices during one-lung ventilation in adult patients undergoing elective thoracic surgery. Modified indices incorporating driving pressure and mechanical power will also be assessed.

No intervention beyond standard clinical care will be applied. The findings of this study may help clarify the clinical utility of non-invasive oxygenation indices for intraoperative monitoring during one-lung ventilation.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patients aged 18 years and older

Patients classified as ASA physical status I-III

Patients scheduled for elective thoracic surgery requiring one-lung ventilation for at least 1 hour intraoperatively

Patients in whom simultaneous arterial blood gas analysis and continuous SpO₂ monitoring can be performed

Disqualifiers

Patients undergoing emergency surgery

Patients younger than 18 years of age

Patients classified as ASA physical status IV or higher

Patients with a history of previous thoracic surgery

Trial population

Adult patients aged 18 years and older with ASA physical status I-III who are scheduled for elective thoracic surgery requiring intraoperative one-lung ventilation for at least one hour. All participants undergo standard perioperative management with simultaneous arterial blood gas analysis and continuous pulse oximetry monitoring during surgery.

Trial design

Design model

Cohort

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

51 Participants
are grouped into 1 trial group
Group A: One-Lung Ventilation Cohort

Trial outcomes

Primary outcomes

1

Correlation between oxygenation indices and oxygen saturation indices

Correlation between invasive oxygenation indices (oxygenation index and its derivatives) and non-invasive oxygen saturation indices (oxygen saturation index and its derivatives) measured during one-lung ventilation.

Time frame
During intraoperative one-lung ventilation

Secondary outcomes

Other outcomes

Sponsors and contacts

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