About this trial
One-lung ventilation is commonly used during thoracic surgery but is frequently associated with impaired oxygenation and altered respiratory mechanics. Traditional oxygenation indices require arterial blood gas analysis and do not fully reflect the mechanical stress applied to the lungs.
This prospective observational study aims to evaluate the correlation between oxygenation indices and oxygen saturation indices during one-lung ventilation in adult patients undergoing elective thoracic surgery. Modified indices incorporating driving pressure and mechanical power will also be assessed.
No intervention beyond standard clinical care will be applied. The findings of this study may help clarify the clinical utility of non-invasive oxygenation indices for intraoperative monitoring during one-lung ventilation.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Patients aged 18 years and older
Patients classified as ASA physical status I-III
Patients scheduled for elective thoracic surgery requiring one-lung ventilation for at least 1 hour intraoperatively
Patients in whom simultaneous arterial blood gas analysis and continuous SpO₂ monitoring can be performed
Disqualifiers
Patients undergoing emergency surgery
Patients younger than 18 years of age
Patients classified as ASA physical status IV or higher
Patients with a history of previous thoracic surgery
Trial population
Adult patients aged 18 years and older with ASA physical status I-III who are scheduled for elective thoracic surgery requiring intraoperative one-lung ventilation for at least one hour. All participants undergo standard perioperative management with simultaneous arterial blood gas analysis and continuous pulse oximetry monitoring during surgery.
Trial design
Cohort
Prospective
Treatments tested in this trial
Not listed
Trial groups
Trial outcomes
Primary outcomes
Correlation between oxygenation indices and oxygen saturation indices
Correlation between invasive oxygenation indices (oxygenation index and its derivatives) and non-invasive oxygen saturation indices (oxygen saturation index and its derivatives) measured during one-lung ventilation.
Sponsors and contacts
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