Cortical Excitability and Typing Performance After Action Observation and Motor Execution

ConditionYoung Adults
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-26
SponsorUniversity of Sharjah

About this trial

Goal:

This study will aim to investigate the effects of different motor stimulation strategies-motor execution (ME) and action observation (AO)-on cortical excitability and typing performance in healthy individuals.

Recruitment:

A total of 60 healthy university students will be recruited and randomly assigned into three groups:

Motor Execution group (n=20) Action Observation group (n=20) Control group (n=20)

Evaluation Tools:

Transcranial Magnetic Stimulation (TMS) using DEYMED DuoMAG XT will be used to measure Resting Motor Threshold (RMT), Motor Evoked Potential (MEP) Amplitude, and MEP Latency of the First Dorsal Interosseous (FDI) muscle.

Online Typing Test will be used to assess typing speed (words per minute) and accuracy (percentage of correct characters).

Intervention:

The ME group will perform a 3-minute typing task. The AO group will observe a 3-minute first-person video of typing. The Control group will not receive any intervention between assessments.

All participants will undergo TMS and typing assessments twice, once before and once after the intervention.

Eligibility criteria

This trial accepts healthy volunteers

Qualifiers

Age between 18 and 26 years

Healthy university students with no known neurological, psychiatric, or musculoskeletal conditions

Intact motor functioning of the upper limbs

Basic typing proficiency using a 10-finger typing method

Disqualifiers

Typing speed less than 16 words per minute

Use of hunt-and-peck or single-finger typing style

History of seizures or epilepsy

Current use of neuroactive medications

Trial design

Design model

Parallel

Treatments tested in this trial

  • Motor Execution Typing Task

    Behavioral

    Participants will perform a 3-minute typing task using custom-designed text that emphasizes index finger use. This task is designed to actively engage the motor cortex and will be administered in a controlled environment using standard posture and equipment. The task aims to elicit changes in cortical excitability, which will be measured pre- and post-intervention using TMS.

  • Action Observation of Typing Task

    Behavioral

    Participants will observe a 3-minute first-person video of an individual typing the standardized text. The video is designed to activate mirror neuron systems through visual engagement with a familiar motor task. It will be shown once in a controlled setting, and post-assessment of cortical excitability will follow immediately after.

Treatment groups

60 Participants
are divided into 3 treatment groups
Group A: MEExperimental treatment 1 intervention
Group B: AOExperimental treatment 1 intervention
Group C: ControlNo intervention 0 interventions

Trial outcomes

Primary outcomes

1

Change in Resting Motor Threshold (RMT)

Resting Motor Threshold (RMT) will be measured using Transcranial Magnetic Stimulation (TMS) targeting the First Dorsal Interosseous (FDI) muscle. RMT is defined as the minimum stimulation intensity required to evoke a measurable motor evoked potential (MEP) of ≥50 µV in at least 5 out of 10 trials.

Time frame
Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)
2

Change in MEP Latency and Amplitude

Motor Evoked Potential (MEP) latency (in milliseconds) and amplitude (in µV) will be assessed using TMS. These measures reflect neural conduction time and the magnitude of cortical response, respectively.

Time frame
Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)
3

Change in Typing Speed (Words Per Minute)

Typing speed will be measured using a standardized online typing platform, expressed in words per minute (WPM). Participants will complete a 3-minute typing task using custom text emphasizing index finger usage.

Time frame
Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)
4

Change in Typing Accuracy

Typing accuracy will be recorded as the percentage of correctly typed characters during a 3-minute standardized typing task using an online platform.

Time frame
Pre-intervention (Day 1) and Post-intervention (within 15 minutes after intervention on Day 2, between 48 hours to a 3-week window)

Secondary outcomes

Other outcomes

Sponsors and contacts

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