About this trial
The purpose of this study is to characterize the cortical connectivity changes in the brain of spastic diplegic children after Selective Dorsal Rhizotomy.
Eligibility criteria
This trial does not accept healthy volunteersQualifiers
Children diagnosis with Spastic Diplegia and having Selective Dorsal Rhizotomy surgery
Disqualifiers
No Selective Dorsal Rhizotomy surgery
Trial design
Single group
Treatments tested in this trial
3Tesla MRI with DTI-MRI and rsfcMRI under general anesthesia
Procedure/Surgery2 post-operative MRI's at 2 months and 12 months
Treatment groups
Trial outcomes
Primary outcomes
Change in Fractional Anisotropy as assessed by brain MRI with diffusion tractography imaging (DTI) sequences
This measure will be used to assess changes in the lower extremity fibers corticopyramidal tract after Selective Dorsal Rhizotomy (SDR).
Change in Mean Diffusivity as assessed by brain MRI with diffusion tractography imaging (DTI) sequences
This measure will be used to assess changes in the lower extremity fibers corticopyramidal tract Selective Dorsal Rhizotomy (SDR).
Change in Radial Diffusivity as assessed by brain MRI with diffusion tractography imaging (DTI) sequences
This measure will be used to assess changes in the lower extremity fibers corticopyramidal tract after Selective Dorsal Rhizotomy (SDR)
Change in Axial Diffusivity as assessed by brain MRI with diffusion tractography imaging (DTI) sequences
This measure will be used to assess changes in the lower extremity fibers corticopyramidal tract after Selective Dorsal Rhizotomy (SDR)
Sponsors and contacts
Click on the lead sponsor to view all of their trials.