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Costotransverse Foramen Block Versus Thoracic Paravertebral Block in Thoracotomy for Lung Cancer

ConditionsCostotransverse Foramen BlockThoracic Paravertebral BlockThoracotomyLung Cancer
Trial statusRecruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age18-65
SponsorNational Cancer Institute, Egypt

About this trial

This study aims to compare the costotransverse foramen block (CTFB) with thoracic paravertebral block (TPVB) in patients undergoing thoracotomy for lung cancer.

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Age > 18 years and ≤ 65 years old.

American Society of Anesthesiologists (ASA) physical status II-III.

Body mass index 18-35 kg/m2.

Patients scheduled for thoracotomies for lung cancer.

Disqualifiers

Patient refusal.

History of sensitivity to local anesthetics.

History of psychological disorders.

Contraindication to regional anesthesia, e.g., local sepsis, pre-existing peripheral neuropathies, and coagulopathy.

Trial design

Design model

Parallel

Treatments tested in this trial

  • Costotransverse foramen block

    Other intervention

    Patients will receive an ipsilateral ultrasound-guided costotransverse foramen block with injection of 20 ml bupivacaine 0.25%.

  • Thoracic paravertebral plane block

    Other intervention

    Patients will receive an ipsilateral ultrasound-guided thoracic paravertebral plane block with injection of 20 ml bupivacaine 0.25%.

Treatment groups

70 Participants
are divided into 2 treatment groups
Group A: CTFB GroupExperimental treatment 1 intervention
Group B: TPVB GroupExperimental treatment 1 intervention

Trial outcomes

Primary outcomes

1

Total morphine consumption

If the visual analog scale (VAS) is ≥ 4, rescue analgesics will be administered in the form of a 4 mg bolus of morphine.

Time frame
24 hours postoperatively

Secondary outcomes

1

Duration of analgesia

Duration of analgesia will be recorded from the end of surgery till first dose of morphine administrated.

Time frame
24 hours postoperatively
2

Degree of pain

Each patient will be instructed about postoperative pain assessment with the visual analog scale (VAS). VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be recorded in post-anesthesia care unit (PACU) and after 1, 6, 12, 24 \& 48 hours postoperatively

Time frame
48 hours postoperatively
3

Intraoperative fentanyl consumption

Intraoperative fentanyl consumption will be recorded.

Time frame
Intraoperatively
4

Mean arterial blood pressure

Mean arterial blood pressure will be recorded before induction of general anesthesia to be defined as the baseline reading. Another reading will be noted immediately before surgical incision and at 20-minute intervals intraoperatively, and then hourly for the next 4 hours postoperatively.

Time frame
4 hours postoperatively

Other outcomes

Sponsors and contacts

Click on the lead sponsor to view all of their trials.

National Cancer Institute, Egypt

Lead sponsor

Source ClinicalTrials.gov
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