Creatine Supplementation in Pediatric Brain Injury
Trial statusNot yet recruiting
Trial phaseNot applicable
Trial typeInterventional
Biological sexAll
Age8-25
SponsorSpaulding Rehabilitation Hospital
About this trial
A study examining the effects of creatine supplementation to improve recovery after brain injury in children and teenagers.
Eligibility criteria
Qualifiers
History of subacute moderate-to-severe brain injury resulting in a new functional impairment, as defined by: Glasgow Coma Scale score (GCS) < 13 points
Subacute brain injury is defined to be < 3 months since index injury
Disqualifiers
Weight < 25 kg
History pre-existing chronic kidney disease (CKD stage ≥ 2), prior kidney transplantation, previous dialysis dependence, or solitary kidney status
Premorbid (pre-brain injury) eGFR < 60
Inability to obtain regular phlebotomy for any reason
Trial design
Treatments tested in this trial
- Creatine monohydrate
- Microcrystalline Cellulose
Treatment groups
46 Participants
are divided into 2 treatment groupsLocations
Sponsors and collaborators
Source ClinicalTrials.gov