Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelodysplastic Syndrome (MDS) Monitored at the Nantes University Hospital

Trial statusRecruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age18+
SponsorNantes University Hospital

About this trial

The aim of the LANA bio-collection is to collect samples from patients with Acute Myeloid Leukemia (AML), Acute Lymphocytic Leukemia (ALL) or or high-risk myelodysplastic syndrome (MDS) to facilitate access to the leukemic or myelodysplastic cells for the research teams of the National Institute of Health and Medical Research (INSERM). To do this, an additional blood or bone marrow sample to those planned in the context of patient care will be collected after signing consent. These samples will then be sent directly to the INSERM teams for immediate analysis with the aim to conduct research aimed at a better understanding of AML, ALL or MDS and improving treatments

Eligibility criteria

This trial does not accept healthy volunteers

Qualifiers

Patient of legal age affected by AML, ALL or MDS regardless of the time of treatment

Patient who has signed the consent form.

Patient affiliated with a social security system.

Disqualifiers

Minor patients.

Adults under guardianship.

Protected persons

Trial population

Patients with high-risk AML, ALL, or MDS managed in the hematology department of the University Hospital of Nantes

Trial design

Design model

Other

Time perspective

Prospective

Treatments tested in this trial

Not listed

Trial groups

1,000 Participants
are grouped into 1 trial group
Group A: Patients with high-risk AML, ALL or MDS

Trial outcomes

Primary outcomes

1

Characterization of the tumor and its microenvironment for AML, ALL or MDS in order to identify novel biomarkers or therapeutic targets

Identify genetic polymorphisms associated with an increased risk of developing AML or ALL

Time frame
One year after inclusion

Secondary outcomes

Other outcomes

Sponsors and contacts

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