Creation of a Biological Collection of BRonchiaI and Pulmonary Tissues From Surgical wastE
Trial statusNot yet recruiting
Trial phaseNot listed
Trial typeObservational
Biological sexAll
Age1-80
SponsorUniversity Hospital, Bordeaux
About this trial
The biological samples and associated data will facilitate the successful implementation of the research collaboration between Bordeaux University Hospital and the University of Bordeaux on the pathophysiology of bronchopulmonary diseases. In the longer term, this research could lead to the discovery of new therapeutic targets for asthma, chronic obstructive pulmonary disease (COPD), pulmonary hypertension, and acute respiratory distress syndrome.
Eligibility criteria
This trial accepts healthy volunteersQualifiers
Male or female
Adult or children
Having required or necessitating, in the context of care or research involving the human person promoted by the Bordeaux University Hospital (ARISE, BIRDIES, ICEBERG, VIRCHILLD) or by Inserm (COBRA), either thoracic surgery such as lobectomy, pneumonectomy or lung transplantation in the Thoracic Surgery Department of the Haut Lévêque Hospital, or bronchial fiberscopy with biopsies and/or bronchial brushing and/or BAL at the children's hospital of the Pellegrin Hospital or at the Haut Lévêque Hospital.
Having received or, for children whose holders of parental authority have received, an information note with the possibility of opposition in accordance with the MR004 (French law - Commission Nationale de l'Informatique et des Libertés (CNIL))
Disqualifiers
Patient or holder of parental authority for children who have expressed their opposition to participation in the research
Trial population
The population includes male and female participants of all ages (adults and children) who are undergoing or require specific thoracic or bronchial procedures, sputum, nasal brushing, blood as part of clinical care or research. These procedures are conducted under the auspices of Bordeaux University Hospital (e.g., ARISE, BIRDIES, ICEBERG, VIRCHILLD) or Inserm (e.g., COBRA).
Trial design
Design model
Cohort
Time perspective
Prospective
Treatments tested in this trial
Fiberscopic samples
Procedure/SurgeryPerform brushing and/or bronchial biopsies and/or BAL and/or aspiration during bronchial fiberscopy and surgical waste during a lobectomy.
Sputum
Procedure/SurgerySputum has been collected for biological analysis.
Nasal brushing
Procedure/SurgeryNasal brushing is a minimally invasive medical procedure used to collect cellular samples from the nasal lining by gently rubbing a small cytology brush against the mucosa.
blood sampling
Procedure/SurgeryBlood sampling is the safe collection of a blood specimen from a vein, finger, or artery to run medical lab tests
Treatment groups
650 Participants
are divided into 3 treatment groupsGroup A: Patient with COPD3 interventions
Group B: Patient with Asthma4 interventions
Group C: Healthy volunteer1 intervention
Trial outcomes
Primary outcomes
1
Describe tobacco consumption
Number pack in years
Time frame
At enrollment2
Describe tobacco statut
Described as either non-smokers, former smokers or current smokers
Time frame
At enrollment3
Description of demographic status
Gender (male or female)
Time frame
At enrollment4
Description of demographic status
Age as years
Time frame
At enrollmentSecondary outcomes
1
Mesure of blood gas parameter
PaO2: arterial pressure in oxygen,
Time frame
At enrollment2
Mesure of blood gas parameter
PaCO2: arterial pressure in carbon dioxide
Time frame
At enrollment3
Mesure of blood gas parameter
pH
Time frame
At enrollmentSponsors and contacts
Click on the lead sponsor to view all of their trials.
Source ClinicalTrials.gov
This trial is not recruiting at the moment. You can still explore other options: